Congenital rubella syndrome overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: :Kalsang Dolma, M.B.B.S.[2]
|
Congenital Rubella Syndrome Microchapters |
|
Differentiating Congenital Rubella Syndrome from other Diseases |
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Congenital rubella syndrome overview On the Web |
|
American Roentgen Ray Society Images of Congenital rubella syndrome overview |
|
Directions to Hospitals Treating Congenital rubella syndrome |
|
Risk calculators and risk factors for Congenital rubella syndrome overview |
Overview
Congenital rubella syndrome (CRS) can occur in a developing fetus of a pregnant woman who has contracted rubella during her first trimester. Problems rarely occur when rubella is contracted by the mother after 20 weeks of gestation.
Pathophysiology
Congenital rubella syndrome results from the spread of infection to fetus by mother during viremic stage. Rubella virus enters fetus through the placenta and cause damage to all germ layers of fetus. This results in rapid death of some cells.
Causes
Congenital rubella syndrome is caused by rubella virus which is a single stranded RNA toga virus.
Epidemiology and Demographics
Congenital rubella syndrome is rare in developed countries with strong immunization programs. It is endemic in other parts of the world.
Treatment
Medical Therapy
There is no specific treatment for congenital rubella syndrome. Symptoms are treated as appropriate. Management for ocular congenital rubella syndrome (CRS) is similar to that for age-related macular degeneration, including counseling, regular monitoring, and the provision of low vision devices, if required.[1]
Surgery
Treatment of newly born babies is focused on management of the complications. Congenital heart defects and cataracts can be corrected by direct surgery.[2]
References
- ↑ Weisinger HS, Pesudovs K (2002). "Optical complications in congenital rubella syndrome". Optometry. 73 (7): 418–24. PMID 12365660.
- ↑ Khandekar R, Sudhan A, Jain BK, Shrivastav K, Sachan R (2007). "Pediatric cataract and surgery outcomes in Central India: a hospital based study". Indian J Med Sci. 61 (1): 15–22. doi:10.4103/0019-5359.29593. PMID 17197734.