Primary biliary cirrhosis other diagnostic studies
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Primary Biliary Cirrhosis Microchapters |
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Differentiating Primary Biliary Cirrhosis from other Diseases |
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Other Diagnostic Studies
Liver Biopsy
Primary biliary cirrhosis is characterized by interlobular bile duct destruction. Histopathologic findings of primary biliary cirrhosis include:[1]
- Inflammation of the bile ducts, characterized by intraepithelial lymphocytes
- Periductal epithelioid granulomata
A liver biopsy is necessary to determine the stage of disease.
ERCP
Abdominal ultrasound or a CT scan is usually performed to rule out blockage to the bile ducts. Previously most suspected sufferers underwent a liver biopsy, and - if uncertainty remained - endoscopic retrograde cholangiopancreatography (ERCP, an endoscopic investigation of the bile duct).