Acid indigestion

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Acid indigestion is a type of indigestion involving an excess of hydrochloric acid in the stomach. Frequent occurrence of acid indigestion can lead to aggravation of the duodenum or to an aggravation of the lining of the stomach, both of which can lead to ulcers which can be life-threatening. However, it is important to note that some 85...95% of all stomach ulcers are caused by infection with the bacterium Helicobacter pylori, and not by excess acidity.

Acid indigestion should be distinguished from heartburn, which typically involves aggravation of the esophagus.

Causes

Common Causes

Common contributors to acid indigestion are:

• Eating foods with too much fat in them.
• Eating foods with too much spice in them.
• Excess consumption of
  • Alcohol
  • Caffeine
• Smoking
• Overeating
• Eating too late in the evening, or eating just before sleeping.

Over the counter remedies (antacids) are available at almost all grocery stores and drugstores. However, a kind of dependence can develop on these medications, and other complications can arise from excess use of antacids.

Causes of Acid Indigestion by Organ System

Cardiovascular	No underlying causes
Chemical / poisoning	4-Chlorodehydromethyltestosterone, Amanita phalloides, Smoking, Sodium dichloroisocyanurate
Dermatologic	No underlying causes
Drug Side Effect	4-Chlorodehydromethyltestosterone, Adefovir (patient information), Atazanavir (patient information), Cholestyramine (patient information), Cholestyramine Resin (patient information), Colofac, Duloxetine, Efavirenz (patient information), Emtricitabine (patient information), Epoetin Alfa Injection (patient information), Fentanyl Skin Patches (patient information), Frovatriptan (patient information), Imatinib (patient information), Interferon Beta-1b Injection (patient information), Lithium (patient information), Meropenem Injection (patient information), Oxycodone and aspirin (patient information), Pergolide (patient information), Pramlintide injection (patient information), Quetiapine (patient information), Rivastigmine (patient information), Simvastatin, Tadalafil, Tiotropium Oral Inhalation (patient information)
Ear Nose Throat	No underlying causes
Endocrine	Primary hyperparathyroidism
Environmental	Multiple chemical sensitivity
Gastroenterologic	Tropical sprue
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	No underlying causes
Infectious Disease	Hookworm
Musculoskeletal / Ortho	No underlying causes
Neurologic	No underlying causes
Nutritional / Metabolic	Diabulimia, Eating fatty foods, Eating just before sleeping, Eating spicy foods, Eating too late in the evening, Excess alcohol consumption, Excess caffeine consumption, Garlic, Indian gooseberry, Overeating, Suillus luteus
Obstetric/Gynecologic	No underlying causes
Oncologic	Ovarian cancer
Opthalmologic	No underlying causes
Overdose / Toxicity	Niacin, Vitamin C
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal / Electrolyte	No underlying causes
Rheum / Immune / Allergy	Oral allergy syndrome
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	Couvade, Gulf War syndrome, SSRI discontinuation syndrome, Trichophagia

Causes of Acid Indigestion in Alphabetical Order

• 4-Chlorodehydromethyltestosterone
• Adefovir
• Amanita phalloides
• Atazanavir
• Cholestyramine
• Cholestyramine Resin)
• Colofac
• Couvade
• Diabulimia
• Duloxetine
• Eating fatty foods
• Eating just before sleeping
• Eating spicy foods
• Eating too late in the evening
• Efavirenz)
• Emtricitabine
• Epoetin Alfa Injection)
• Excess alcohol consumption
• Excess caffeine consumption
• Fentanyl Skin Patches
• Frovatriptan
• Garlic
• Gulf War syndrome
• Hookworm
• Imatinib
• Indian gooseberry
• Interferon Beta-1b Injection
• Lithium
• Meropenem Injection
• Multiple chemical sensitivity
• Niacin
• Oral allergy syndrome
• Ovarian cancer
• Overeating
• Oxycodone and aspirin
• Pergolide
• Pramlintide injection
• Primary hyperparathyroidism
• Quetiapine)
• Rivastigmine
• Simvastatin
• Smoking
• Sodium dichloroisocyanurate
• SSRI discontinuation syndrome
• Suillus luteus
• Tadalafil
• Tiotropium Oral Inhalation
• Trichophagia
• Tropical sprue
• Vitamin C