Cardiovascular
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Abdominal aortic aneurysm rupture, infective endocarditis, intestinal lymphangiectasia, ischemic colitis, malignant hypertension, mesenteric artery ischemia, pancreatic ischemia, pulmonary arteriovenous malformations, pulmonary embolism, pulmonary infarction, purulent pericarditis, rheumatoid vasculitis, splenic artery aneurysm, splenic artery embolization, splenic infarction, systemic vasculitis
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Chemical/Poisoning
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Algal toxin in shellfish, aluminum toxicity, arsenic poisoning, cadmium toxicity, chromium poisoning, copper poisoning, ecstasy overdose, ethylene glycol poisoning, food poisoning, gold, heavy metals, iron poisoning, lead poisoning, mercury poisoning, methanol, organophosphate poisoning, saw palmetto, scorpion sting, silver poisoning, toxic mushrooms
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Dental
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No underlying causes
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Dermatologic
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Scarlet fever, scleroderma
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Drug Side Effect
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Aspirin, atorvastatin, azathioprine, cerivastatin, colchicine toxicity, cyclosporin, diclofenac, didanosine, estrogen, fentanyl toxicity, fluvastatin, furosemide, hydroxyurea, ibuprofen, indomethacin, L-asparaginase, malignant hyperthermia, mercaptopurine (6-MP), methotrexate, metronidazole, naproxen, nonsteroidal anti-inflammatory drugs (NSAIDs), pentamidine, propylthiouracil, Reye's syndrome, salicylates, stavudine, steroid abuse, sulindac, tetracycline, thiazides, thrombolytic therapy, tramadol toxicity, valproic acid, valsartan, vinblastine, vincristine, vitamin D toxicity, warfarin, zalcitabine
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Ear Nose Throat
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No underlying causes
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Endocrine
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Carcinoid, diabetic ketoacidosis, hyperlipidemia (types I, IV, V), hyperparathyroidism, MODY syndrome, multiple endocrine neoplasia type 1, Zollinger-Ellison syndrome
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Environmental
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Organophosphate poisoning, saw palmetto
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Gastroenterologic
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Abdominal compartment syndrome, acinic cell carcinoma, acute pancreatitis, acute diverticulitis, atraumatic splenic rupture, autoimmune gastritis, autoimmune pancreatitis, Bannayan-Zonana syndrome, bile reflux disease, bulimia nervosa, celiac disease, chronic constipation, collagenous colitis, colon cancer, colonic lymphoma, hereditary spherocytosis, congestive splenomegaly, crohn's disease, cystic metastasis to the spleen, eosinophilic gastroenteritis, familial adenomatous polyposis, Felty's syndrome, gastric carcinoma, gastrinoma, gastritis, Gaucher disease, gout, hepatorenal syndrome, hiatus hernia, hyperlipidemia (types I, IV, V), intestinal lymphangiectasia, intestinal pseudo-obstruction, intussusception, irritable bowel syndrome, ischemic colitis, islet cell adenoma, malignant peritoneal mesothelioma, ménétrier's disease, milk-alkali syndrome, pancreatic cystic neoplasms, pancreatic tail cancer, peptic ulcer disease, perforated gastric ulcer, peritonitis, pernicious anemia, Peutz-Jeghers syndrome, polycystic kidney disease with splenic cysts, porphyria, pseudocysts cystic splenosis, scarlet fever, scleroderma, somatostatinoma, splenic abscess, splenic hematoma and laceration, splenic infarction, splenic lymphoma, splenosis, stress ulcer, subphrenic abscess, traumatic splenic rupture, typhoid fever, ulcerative colitis, viral gastroenteritis, visceral hamartoma, visceral hemangioma, volvulus, wandering spleen syndrome, Zollinger-Ellison syndrome
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Genetic
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Alpha-1-antitrypsin deficiency, Alport syndrome, apolipoprotein C deficiency, beta thalassemia major, colon atresia, cystic fibrosis, cystinuria, Dent's disease, familial adenomatous polyposis, Gaucher disease, hereditary angio-oedema, homocystinuria, hyperlipidemia (types I, IV, V), Meckel syndrome, polycystic kidney disease with splenic cysts, porphyria, primary hyperoxaluria, sickle cell anemia, tuberous sclerosis, Turner syndrome, Von Hippel-Lindau Disease, WAGR syndrome, Williams syndrome
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Hematologic
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Acquired hemolytic anemia, antiphospholipid syndrome, beta thalassemia major, chronic lymphocytic leukemia, chronic myeloid leukemia, hereditary spherocytosis, cryoglobulinemia, essential thrombocytosis, hairy cell leukemia, lymphomas, MALT lymphoma, mastocytosis, myelofibrosis, myoglobinuria , plasma cell leukemia, polycythemia vera, porphyria, Sézary syndrome, sickle cell anemia, Waldenstrom macroglobulinemia
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Iatrogenic
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Chromoendoscopy, cryoablation, exercise-induced gastrointestinal bleeding, gas following laparoscopy, gastric surgery, intra abdominal adhesions, large volume thoracentesis, magnetic resonance cholangiopancreatography, milk-alkali syndrome, nasogastric and nasoenteric tubes, pancreaticoduodenectomy (Whipple procedure), percutaneous abdominal biopsy, peritoneal dialysis, post-ERCP perforation, post-traumatic cysts, precut (access) papillotomy, radiation therapy, referred pain, splenic artery embolization, vitamin D toxicity
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Infectious Disease
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AIDS with mycobacterium avium complex, AIDS-associated nephropathy, AIDS-related cytomegalovirus, amebic dysentery, ascariasis, babesiosis, bacillary dysentery, botryomycosis, brucellosis, campylobacter jejuni, candidiasis, chronic malaria, giardiasis, helicobacter pylori infection, histoplasmosis, hydatid (echinococcal) cysts, infectious mononucleosis, infective endocarditis, inflammatory pleural effusions, intestinal worm infestation, kala-azar (visceral leishmaniasis), mediterranean spotted fever, miliary tuberculosis, mumps, peritonitis, pneumonia, post streptococcal glomerulonephritis, psittacosis, purulent pericarditis, pyelonephritis, renal abscess, perinephric abscess, renal mucormycosis, renal tuberculosis, shingles, splenic abscess, staphylococcal toxic shock syndrome, streptococcal toxic shock syndrome, subphrenic abscess, traveler's diarrhea, tropical splenomegaly syndrome, typhoid fever, vibrio parahaemolyticus, viral gastroenteritis, viral hemorrhagic fevers, Weil syndrome, yellow fever
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Musculoskeletal/Orthopedic
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Gout
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Neurologic
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Meckel syndrome
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Nutritional/Metabolic
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Carbohydrate-deficient glycoprotein syndrome, cystinuria, Gaucher Disease, homocystinuria, hyperuricaemia, oxalosis
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Obstetric/Gynecologic
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Eclampsia, endometriosis, gestational trophoblastic disease
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Oncologic
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Acinic cell carcinoma, Bannayan-Zonana syndrome, chronic lymphocytic leukemia, chronic myeloid leukemia, colon cancer, colonic lymphoma, cystic metastasis to the spleen, Denys-Drash syndrome, essential thrombocytosis, familial adenomatous polyposis, gastric carcinoma, gastrinoma, hairy cell leukemia, islet cell adenoma, malignant peritoneal mesothelioma, MALT lymphoma, mastocytosis, ménétrier's disease, myelofibrosis, pancreatic tail cancer, Peutz-Jeghers syndrome, plasma cell leukemia, polycythemia vera, renal angiosarcoma, renal cell carcinoma, Sézary syndrome, somatostatinoma, splenic lymphoma, tuberous sclerosis, tumor lysis syndrome, visceral hamartoma, visceral hemangioma, Von Hippel-Lindau disease, WAGR syndrome, Waldenstrom macroglobulinemia, Wilms' tumor
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Ophthalmologic
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No underlying causes
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Overdose/Toxicity
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Cocaine overdose, contrast agents, fentanyl toxicity, steroid abuse, tramadol toxicity
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Psychiatric
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Bulimia nervosa, intestinal pseudo-obstruction, irritable bowel syndrome, stress ulcer
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Pulmonary
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Alpha-1-antitrypsin deficiency, cystic fibrosis, empyema, Goodpasture syndrome, inflammatory pleural effusions, pneumonia, pulmonary arteriovenous malformations, pulmonary embolism, pulmonary infarction, systemic lupus erythematosus, Wegener's granulomatosis
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Renal/Electrolyte
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Alport syndrome, cystinuria, Dent's disease, Denys-Drash syndrome, Goodpasture syndrome, homocystinuria, Meckel syndrome, medullary cystic kidney disease, membranoproliferative glomerulonephritis, myoglobinuria, nephrocalcinosis, oxalosis, polycystic kidney disease with splenic cysts, post streptococcal glomerulonephritis, pyelonephritis, reflux nephropathy, perinephric abscess, renal angiosarcoma, renal cell carcinoma, renal mucormycosis, renal tuberculosis, renal tubular acidosis, scleroderma, systemic lupus erythematosus, tuberous sclerosis, tubulointerstitial nephritis, Turner syndrome, urinary outflow obstruction, vesicoureteral reflux, Von Hippel-Lindau disease, WAGR syndrome, Wegener's granulomatosis, Weil syndrome, Williams syndrome, Wilms tumor, xanthogranulomatous pyelonephritis
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Rheumatology/Immunology/Allergy
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Allergic gastroenteropathy, autoimmune gastritis, autoimmune pancreatitis, crohn's disease, cryoglobulinemia, Felty's syndrome, food intolerance, hereditary angio-oedema, pernicious anemia, Reye's syndrome, rheumatoid vasculitis, scarlet fever, systemic lupus erythematosus, systemic vasculitis, ulcerative colitis, Wegener's granulomatosis
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Sexual
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Denys-Drash syndrome, Turner syndrome
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Trauma
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Electrical burns, rib fractures, splenic hematoma and laceration, traumatic splenic rupture
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Urologic
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No underlying causes
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Miscellaneous
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Alcohol ingestion, chronic constipation, excessive caffeine, idiopathic, spicy food, splenosis
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