Focal segmental glomerulosclerosis epidemiology and demographics
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Epidemiology & Demographics
Focal segmental glomerulosclerosis (FSGS) is considered the most common cause of nephrotic syndrome worldwide and the most common primary renal cause of end-stage renal disease (ESRD) in whites and blacks, contributing to approximately 2% of ESRD.[1]
FSGS is more common in blacks. It accounts for approximately 35% of nephrotic syndromes in all cases and approximately 50% of nephrotic syndrome in blacks.[2] The disease is considered a disease of the adult population (vs. minimal change disease which is much more common among children). In a 21-year follow-up study that excludes HIV-associated nephropathy, the median age of FSGS ESRD is 40-49 years in black adults and 70-79 in white and Asian adults.[1] The male to female ratio is 1.5-2 to 1.[1]
References
- ↑ 1.0 1.1 1.2 Kitiyakara C, Eggers P, Kopp JB (2004). "Twenty-one-year trend in ESRD due to focal segmental glomerulosclerosis in the United States". Am J Kidney Dis. 44 (5): 815–25. PMID 15492947.
- ↑ Hogg R, Middleton J, Vehaskari VM (2007). "Focal segmental glomerulosclerosis--epidemiology aspects in children and adults". Pediatr Nephrol. 22 (2): 183–6. doi:10.1007/s00467-006-0370-5. PMC 1764601. PMID 17151873.