Sandbox/0319

FDA-Labeled Indications and Dosage (Adult)
Prophylaxis of Ischemic Complications in Unstable Angina and Non-Q-Wave Myocardial Infarction
▸ Fragmin injection 120 IU/kg SC q12h (≤10,000 IU) for 5—8 days with concurrent Aspirin 75—165 mg PO q24h
Prophylaxis of Venous Thromboembolism Following Hip Replacement Surgery
▸ Fragmin injection 2500 IU SC 4—8 hours POSToperatively followed by 5000 IU SC q24h for 5—10 days OR ▸ Fragmin injection 2500 IU SC 2 hours PREoperatively and 4—8 hours POSToperatively followed by 5000 IU SC q24h for 5—10 days OR ▸ Fragmin injection 5000 IU SC 10—14 hours PREoperatively and 4—8 hours POSToperatively followed by q24h for 5—10 days
Prophylaxis of Venous Thromboembolism Following Abdominal Surgery
▸ Fragmin injection 2500 IU SC q24h PREoperatively followed by q24h for 5—10 days OR ▸ Fragmin injection 5000 IU SC q24h for 5—10 days (starting the evening prior to sugery) [High Risk Patient] OR ▸ Fragmin injection 2500 IU SC PREoperatively and 2500 IU SC 12 hours later followed by 5000 IU SC q24h for 5—10 days [High Risk Patient]
Medical Patients with Severely Restricted Mobility During Acute Illness
▸ Fragmin injection 5000 IU SC q24h for 12—14 days
Extended Treatment of Symptomatic Venous Thromboembolism in Patients with Cancer
▸ Fragmin injection 200 IU/kg SC q24h (≤18,000 IU) for 30 days followed by 150 IU/kg SC q24h from months 2—6