Ebola laboratory tests
Ebola Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Michael Maddaleni, B.S.; Guillermo Rodriguez Nava, M.D. [2]
Overview
Ebola would be categorized as a viral hemorrhagic fever. Antigen-capture enzyme-linked immunosorbent assay (ELISA) testing, IgM ELISA, polymerase chain reaction (PCR), and virus isolation can be used to diagnose a case of Ebola HF within a few days of the onset of symptoms. Persons tested later in the course of the disease or after recovery can be tested for IgM and IgG antibodies; the disease can also be diagnosed retrospectively in deceased patients by using immunohistochemistry testing, virus isolation, or PCR.[1]
Laboratory Findings
There are no specific laboratory findings of Ebola virus disease, the following table shows some nonspecific usually found:[2]
Test | Findings |
---|---|
White blood cells count | Leucopenia Lymphopenia Neutrophilia |
Blood smear | Left shift Atypical lymphocytes |
Liver function tests | Raised aspartate aminotransferase Raised alanine aminotransferase Extended prothrombin time Extended partial thromboplastin time |
Proteins | Hyperproteinemia |
Urinalysis | Proteinuria |
References
- ↑ "Ebola Hemorrhagic Fever Information Packet" (PDF).
- ↑ Feldmann H, Geisbert TW (2011). "Ebola haemorrhagic fever". Lancet. 377 (9768): 849–62. doi:10.1016/S0140-6736(10)60667-8. PMC 3406178. PMID 21084112.