Abacavir lamivudine dosage and administration

Abacavir lamivudine
EPZICOM ® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]

Dosage And Administration

• A Medication Guide and Warning Card that provide information about recognition of hypersensitivity reactions should be dispensed with each new prescription and refill.
• EPZICOM can be taken with or without food.

Adult Patients

The recommended oral dose of EPZICOM for adults is one tablet daily, in combination with other antiretroviral agents.

Dosage Adjustment

Because it is a fixed-dose combination, EPZICOM should not be prescribed for:

• patients requiring dosage adjustment such as those with creatinine clearance <50 mL/min,
• patients with hepatic impairment.

Use of EPIVIR® (lamivudine) Oral Solution or Tablets and ZIAGEN® (abacavir sulfate) Oral Solution may be considered.

References

Adapted from the FDA Package Insert.