Cadexomer iodine

	WikiDoc Resources for Cadexomer iodine
Articles
Most recent articles on Cadexomer iodine Most cited articles on Cadexomer iodine Review articles on Cadexomer iodine Articles on Cadexomer iodine in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Cadexomer iodine Images of Cadexomer iodine Photos of Cadexomer iodine Podcasts & MP3s on Cadexomer iodine Videos on Cadexomer iodine
Evidence Based Medicine
Cochrane Collaboration on Cadexomer iodine Bandolier on Cadexomer iodine TRIP on Cadexomer iodine
Clinical Trials
Ongoing Trials on Cadexomer iodine at Clinical Trials.gov Trial results on Cadexomer iodine Clinical Trials on Cadexomer iodine at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Cadexomer iodine NICE Guidance on Cadexomer iodine NHS PRODIGY Guidance FDA on Cadexomer iodine CDC on Cadexomer iodine
Books
Books on Cadexomer iodine
News
Cadexomer iodine in the news Be alerted to news on Cadexomer iodine News trends on Cadexomer iodine
Commentary
Blogs on Cadexomer iodine
Definitions
Definitions of Cadexomer iodine
Patient Resources / Community
Patient resources on Cadexomer iodine Discussion groups on Cadexomer iodine Patient Handouts on Cadexomer iodine Directions to Hospitals Treating Cadexomer iodine Risk calculators and risk factors for Cadexomer iodine
Healthcare Provider Resources
Symptoms of Cadexomer iodine Causes & Risk Factors for Cadexomer iodine Diagnostic studies for Cadexomer iodine Treatment of Cadexomer iodine
Continuing Medical Education (CME)
CME Programs on Cadexomer iodine
International
Cadexomer iodine en Espanol Cadexomer iodine en Francais
Business
Cadexomer iodine in the Marketplace Patents on Cadexomer iodine
Experimental / Informatics
List of terms related to Cadexomer iodine

Cadexomer iodine
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	D03AX01 (WHO) ;
Identifiers
CAS Number	94820-09-4 ;
ChemSpider	NA ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
(what is this?) (verify)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cadexomer iodine is an iodophor that is produced by the reaction of dextrin with epichlorhydrin coupled with ion-exchange groups and iodine. It is a water-soluble modified starch polymer containing 0.9% iodine, calculated on a weight-weight basis, within a helical matrix.^[1]

History

Cadexomer iodine was developed in the early 1980s in Sweden by Perstorp AB, and given the name Iodosorb. The product was shown to be effective in the treatment of venous ulcers,.^[2]^[3] More recently, it has been shown in studies in animals and humans that, unlike the iodophor povidone-iodine, Iodosorb causes an acceleration of the healing process in chronic human wounds. This is due to an increase in epidermal regeneration and epithelialization in both partial-thickness and full-thickness wounds.^[4] In this way cadexomer iodine acts as a cicatrizant.

Properties

When formulated as a topical wound dressing Iodosorb adsorbs exudate and particulate matter from the surface of granulating wounds and, as the dressing becomes moist, iodine is released. The product thus has the dual effect of cleansing the wound and exerting a bactericidal action.

Uses

In addition to other manufacturers, Smith & Nephew distributes cadexomer iodine as Iodosorb and Iodoflex in many countries of the world for the treatment and healing of various types of wounds. The dosage forms are a paste dressing, an ointment and a gel, all of which contain 0.9% iodine.

References

↑ Merck Index, 14th Edition, p262 Merck & Co. Inc.
↑ Skog, E. et al. (1983). A randomized trial comparing cadexomer iodine and standard treatment in the out-patient management of chronic venous ulcers. British Journal of Dermatology 109, 77. PMID 6344906
↑ Ormiston, M.C., Seymour, M.T., Venn, G.E., Cohen, R.I. and Fox, J.A. (1985). Controlled trial of Iodosorb in chronic venous ulcers. British Medical Journal (Clinical Research Edition) 291, 308-310. PMID 3962169
↑ Drosou Anna, Falabella Anna, and Kirsner Robert S. (2003) Antiseptics on Wounds: An area of controversy. Wounds 159(5) 149-166. http://cme.medscape.com/viewarticle/456300_2 Retrieved 02/03/2009

Template:Preparations for treatment of wounds and ulcers

[1] Merck Index, 14th Edition, p262 Merck & Co. Inc.

[2] Skog, E. et al. (1983). A randomized trial comparing cadexomer iodine and standard treatment in the out-patient management of chronic venous ulcers. British Journal of Dermatology 109, 77. PMID 6344906

[3] Ormiston, M.C., Seymour, M.T., Venn, G.E., Cohen, R.I. and Fox, J.A. (1985). Controlled trial of Iodosorb in chronic venous ulcers. British Medical Journal (Clinical Research Edition) 291, 308-310. PMID 3962169

[4] Drosou Anna, Falabella Anna, and Kirsner Robert S. (2003) Antiseptics on Wounds: An area of controversy. Wounds 159(5) 149-166. http://cme.medscape.com/viewarticle/456300_2 Retrieved 02/03/2009

[1]

[2]

[3]

[4]