Capillary leak syndrome physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S

Overview

Patients with capillary leak syndrome present with generalized edema, weight gain, fatigue, and body aches. Physical examination is remarkable from hypotension, rash, pruritus, flushing, jaw claudication. Lung examination may reveal wheezing and prolonged expiratory phase. Cardiac examination may reveal tachycardia, weak peripheral pulses, muffled heart sounds on auscultation due to underlying pericardial effusion, pulsus paradoxus, and pericardial friction rub. The patient may also present with abdominal distention, tenderness, and fluid thrill.

Physical Examination

Patient with capillary leak syndrome usually presents with generalized edema fatigued, and body aches. Physical examination is usually remarkable for hypotension, pleural and pericardial effusion.

Appearence of the Patient

• Partial or generalized edema may be seen.
• Weight gain

Vitals

• Low blood pressure (hypotension)

Skin

• Generalized edema or anasarca
• Rash
• Pruritus
• Flushing

HEENT

• Jaw claudication

Neck

• Unremarkable

Lungs

• Wheezing may be present
• Prolonged expiratory phase

Heart

• Tachycardia
• Weak peripheral pulses
• Muffled heart sounds on auscultation due to underlying pericardial effusion
• Pulsus Paradoxus
• Pericardial friction rub

Abdomen

• Abdominal tenderness
• Abdominal distention
• Fluid thrill

Extremities

• Generalized edema