Cerebral palsy MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Iqra Qamar M.D.[2]
Overview
MRI is the diagnostic neuroimaging study of choice especially for older children and is preferred over CT scan. The diagnostic yield of MRI depends upon the type of CP (mixed > quadriplegic > hemiplegic > diplegic > ataxic > dyskinetic) and the timing of birth. MRI findings in patients with CP may include hypoxic-ischemic lesions (eg, periventricular leukomalacia-PVL), cortical malformations and lesions of the basal ganglia.
MRI
- MRI is the diagnostic neuroimaging study of choice especially for older children.[1][2][3][4][5]
- MRI is preferred over CT due to
- Higher diagnostic yield
- Role in finding out the etiology and timing of insult
- The diagnostic yield of MRI depends upon:
- MRI findings in patients with CP include:
- Hypoxic-ischemic lesions (eg, periventricular leukomalacia-PVL)
- Cortical malformations
- Lesions of the basal ganglia (bilateral thalami)
- MRI may show:
- Myelination for a given age
- A tethered spinal cord
- MRI is found to be abnormal in 90% of children with cerebral palsy.[6]
- MRI has an important role in predicting neurodevelopmental outcomes in preterm infants.[7]
- MRI may be normal in cerebral palsy- does not exclude the diagnosis and require exclusion of metabolic and genetic etiologies
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References
- ↑ Ashwal S, Russman BS, Blasco PA, Miller G, Sandler A, Shevell M, Stevenson R (2004). "Practice parameter: diagnostic assessment of the child with cerebral palsy: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society". Neurology. 62 (6): 851–63. PMID 15037681.
- ↑ Truwit CL, Barkovich AJ, Koch TK, Ferriero DM (1992). "Cerebral palsy: MR findings in 40 patients". AJNR Am J Neuroradiol. 13 (1): 67–78. PMID 1595496.
- ↑ Krägeloh-Mann I, Petersen D, Hagberg G, Vollmer B, Hagberg B, Michaelis R (1995). "Bilateral spastic cerebral palsy--MRI pathology and origin. Analysis from a representative series of 56 cases". Dev Med Child Neurol. 37 (5): 379–97. PMID 7768338.
- ↑ Miller G, Cala LA (1989). "Ataxic cerebral palsy--clinico-radiologic correlations". Neuropediatrics. 20 (2): 84–9. doi:10.1055/s-2008-1071271. PMID 2739880.
- ↑ "Bilateral lesions of thalamus and basal ganglia: origin and outcome - Krägeloh-Mann - 2007 - Developmental Medicine & Child Neurology - Wiley Online Library".
- ↑ Bax M, Tydeman C, Flodmark O (2006). "Clinical and MRI correlates of cerebral palsy: the European Cerebral Palsy Study". JAMA. 296 (13): 1602–8. doi:10.1001/jama.296.13.1602. PMID 17018805.
- ↑ Woodward LJ, Anderson PJ, Austin NC, Howard K, Inder TE (2006). "Neonatal MRI to predict neurodevelopmental outcomes in preterm infants". N. Engl. J. Med. 355 (7): 685–94. doi:10.1056/NEJMoa053792. PMID 16914704.