Cryptogenic organizing pneumonia natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
The symptoms of cryptogenic organizing pneumonia usually develop in the fifth or sixth decade of life and start with symptoms such as a cough, dyspnea, and weight loss. Cryptogenic organizing pneumonia patients have the good prognosis after the course of corticosteroids. Fatal outcome of cryptogenic organizing pneumonia is very rare.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of cryptogenic organizing pneumonia usually develop in the fifth or sixth decade of life and start with symptoms such as a cough, dyspnea, and weight loss.
- Cryptogenic organizing pneumonia patients have the good prognosis after the course of corticosteroids. Fatal outcome of cryptogenic organizing pneumonia is very rare.
Complications
- There are no complications associated with cryptogenic organizing pneumonia but there are complications associated with corticosteroids treatment.[1]
- Complications of long-term treatment with corticosteroids therapy are:[2]
- Weight gain
- Decreased in bone density
- Muscle weakness
- Hyperlipidemia
- Growth suppression
- Thining of skin
- Diabetes
Prognosis
- Prognosis is generally good after the treatment with corticosteroids.
- Fatal outcome of cryptogenic organizing pneumonia is rare.[3]
References
- ↑ Lazor R, Vandevenne A, Pelletier A, Leclerc P, Court-Fortune I, Cordier JF (August 2000). "Cryptogenic organizing pneumonia. Characteristics of relapses in a series of 48 patients. The Groupe d'Etudes et de Recherche sur les Maladles "Orphelines" Pulmonaires (GERM"O"P)". Am. J. Respir. Crit. Care Med. 162 (2 Pt 1): 571–7. doi:10.1164/ajrccm.162.2.9909015. PMID 10934089.
- ↑ Buchman AL (October 2001). "Side effects of corticosteroid therapy". J. Clin. Gastroenterol. 33 (4): 289–94. PMID 11588541.
- ↑ Kim M, Cha SI, Seo H, Shin KM, Lim JK, Kim H, Yoo SS, Lee J, Lee SY, Kim CH, Park JY (July 2015). "Predictors of Relapse in Patients with Organizing Pneumonia". Tuberc Respir Dis (Seoul). 78 (3): 190–5. doi:10.4046/trd.2015.78.3.190. PMC 4499585. PMID 26175771.