Dextro-transposition of the great arteries causes

Dextro-transposition of the great arteries Microchapters
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Overview
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Pathophysiology
Causes
Differentiating dextro-transposition of the great arteries from other Diseases
Epidemiology and Demographics
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Pre-natal dextro-transposition of the great arteries
Post-natal dextro-transposition of the great arteries
Infants with dextro-transposition of the great arteries
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
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Laboratory Findings
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Echocardiography or Ultrasound
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Case #1
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [5]

Overview

The causes of most congenital heart defects are unknown.

Causes

The cause of most congenital heart defects is unknown. Factors in the mother that may increase the risk of this condition include:

• Age over 40
• Alcoholism
• Diabetes
• Prenatal nutrition
• Rubella or other viral illness during pregnancy
• Generally, TGA is not known to be associated with any specific single gene defect, but some studies have shown possible genetic association in some cases of TGA, involving deletions of chromosome 22q11.