Endometrial hyperplasia causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Swathi Venkatesan, M.B.B.S.[2]

Overview

Endometrial hyperplasia is caused by high levels of estrogens, combined with insufficient levels of the progesterone-like hormones which ordinarily counteract estrogen's proliferative effects on this tissue.

Causes

• Endometrial hyperplasia is caused by high levels of estrogens, combined with insufficient levels of the progesterone-like hormones which ordinarily counteract estrogen's proliferative effects on this tissue.
• High estrogen may be caused by:
  • Obesity
  • Polycystic ovarian syndrome
  • Estrogen producing tumors (e.g. granulosa cell tumor)
  • Estrogen replacement therapy