Familial adenomatous polyposis history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]
Overview
The majority of patients with familial adenomatous polyposis (FAP) are asymptomatic till colorectal cancer happens. Common symptoms of familial adenomatous polyposis are gastrointestinal bleeding, pain, and altered bowel habits. Patients with FAP may experience fatigue following occult bleeding.
History and Symptoms
The majority of patients with familial adenomatous polyposis are asymptomatic till the development of colorectal cancer.
History
Patients with familial adenomatous polyposis may have a positive:[1]
- Family history of similar condition
- Family history of colorectal cancer
Common Symptoms
Common symptoms of familial adenomatous polyposis are:[1]
- Gastrointestinal bleeding
- Abdominal pain
- Diarrhea
- Altered bowel habit
- Tenesmus
- Obstruction
- Fatigue due to iron deficiency anemia
- Weight loss due to colorectal cancer
Extracolonic manifestations
Patients with familial adenomatous polyposis may present with the following extracolonic manifestations including:[2]
- A swelling or lump due to desmoid tumor of the abdominal cavity which might be with or without pain
- Duodenal adenomas in 50-90% of patients
- Carcinomas
References
- ↑ 1.0 1.1 King, John E.; Dozois, Roger R.; Lindor, Noralane M.; Ahlquist, David A. (2000). "Care of Patients and Their Families With Familial Adenomatous Polyposis". Mayo Clinic Proceedings. 75 (1): 57–67. doi:10.4065/75.1.57. ISSN 0025-6196.
- ↑ Griffioen G, Bus PJ, Vasen HF, Verspaget HW, Lamers CB (1998). "Extracolonic manifestations of familial adenomatous polyposis: desmoid tumours, and upper gastrointestinal adenomas and carcinomas". Scand. J. Gastroenterol. Suppl. 225: 85–91. PMID 9515758.