Fanconi anemia surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shyam Patel [2]
Overview
There is no surgical treatment of Fanconi anemia.
Surgery
There is no surgical treatment of Fanconi anemia. However elective splenectomy and bone marrow transplant are end-stage therapies for Fanconi anemia, as is true for any other aplastic anemia.[1][2][3]
References
- ↑ Guan J, Fransson S, Siaw JTT, Treis D, Van den Eynden J, Chand D; et al. (2018). "Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib". Cold Spring Harb Mol Case Stud. doi:10.1101/mcs.a002550. PMID 29907598.
- ↑ Kulanuwat S, Jungtrakoon P, Tangjittipokin W, Yenchitsomanus PT, Plengvidhya N (2018). "Fanconi anemia complementation group C protection against oxidative stress‑induced β‑cell apoptosis". Mol Med Rep. doi:10.3892/mmr.2018.9163. PMID 29901137.
- ↑ Verhagen CVM, Vossen DM, Borgmann K, Hageman F, Grénman R, Verwijs-Janssen M; et al. (2018). "Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma". Oncotarget. 9 (26): 18198–18213. doi:10.18632/oncotarget.24797. PMC 5915066. PMID 29719599.