Fat embolism syndrome laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Feham Tariq, MD [2]
Overview
Laboratory tests are not done commonly to diagnose fat embolism. However, the most commonly seen findings are anemia, thrombocytopenia and lipidura.
Laboratory Findings
Common Laboratory Findings:
The most commonly seen laboratory findings in fat embolism include:
In some cases, fat embolism syndrome is associated with elevations in the following laboratory values:[1][2]
- Plasma PLA2 (phospholipase A2)
- Nitrate/nitrite
- Methylguanidine
- TNF-α (tumour necrosis factor-α)
- IL-1β (interleukin-1β)
- IL-10 (interleukin-10)
- IL-6 (interleukin-6)[3]
References
- ↑ Kao, Shang Jyh; Yeh, Diana Yu-Wung; Chen, Hsing I. (2007). "Clinical and pathological features of fat embolism with acute respiratory distress syndrome". Clinical Science. 113 (6): 279–285. doi:10.1042/CS20070011. ISSN 0143-5221.
- ↑ Bulger EM, Smith DG, Maier RV, Jurkovich GJ (1997). "Fat embolism syndrome. A 10-year review". Arch Surg. 132 (4): 435–9. PMID 9108767.
- ↑ Prakash S, Sen RK, Tripathy SK, Sen IM, Sharma RR, Sharma S (2013). "Role of interleukin-6 as an early marker of fat embolism syndrome: a clinical study". Clin Orthop Relat Res. 471 (7): 2340–6. doi:10.1007/s11999-013-2869-y. PMC 3676609. PMID 23423626.