HELLP syndrome laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Laboratory Findings

• Complete blood count- Platelet counts may be low.
• Liver enzymes- Liver function tests (liver enzymes) may be high.
• Renal function and electrolytes
• Coagulation studies.
• Often, fibrin degradation products (FDPs) are determined, which can be elevated.
• Lactate dehydrogenase is a marker of hemolysis and is elevated (>600 U/liter).
• Proteinuria is present but can be mild.
• A positive D-dimer test in the presence of preeclampsia has recently been reported to be predictive of patients who will develop HELLP syndrome. D-dimer is a more sensitive indicator of subclinical coagulpathy and may be a positive before coagulation studies are abnormal.