Hemophilia A secondary prevention
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fahd Yunus, M.D. [2]
Overview
Secondary prevention for Hemophilia is aimed at preventing spontaneous or excessive bleeds in patients who are high risk, and relies on the use of recombinant clotting factor VIII/ IX to prevent bleeding episodes.
Secondary Prevention
Secondary preventive measures to avoid Hemophilia A and B include the following:
- Patients should be counseled on safe practices and routine accident prevention.
- Patients with moderate-to-severe hemophilia may be managed with prophylactic transfusions of recombinant clotting factor VIII/ IX in order to prevent bleeding episodes.[1] The goal of prophylaxis is usually to keep clotting factor levels at 1 percent or greater at all times.[2]
- Routine prophylactic transfusions are not recommended for patients with mild hemophilia.
References
- ↑ Franchini M, Mannucci PM (2012). "Past, present and future of hemophilia: a narrative review". Orphanet J Rare Dis. 7: 24. doi:10.1186/1750-1172-7-24. PMC 3502605. PMID 22551339.
- ↑ Prophylaxis: Administration and dosing schedules – World Federation of Hemophilia. Available at http://www.wfh.org/en/abd/prophylaxis/prophylaxis-administration-and-dosing-schedules. Accessed on Sept 20, 2016