Human respiratory syncytial virus epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Bassel Almarie M.D.[2]
Epidemiology and Demographics
Incidence
- In the 2016–2020 season, the incidence of RSV-associated hospitalizations was estimated to be 42-53 per 100,000 individuals.[1]
- In the 2022-2023 season, the incidence of RSV-associated hospitalizations was estimated to be 43.4 per 100,000 individuals.[2]
Age
- RSV infection can occur in patients of all ages.
- Infants and young children are most commonly affected by RSV.
- 55% of RSV cases occur in individuals under 1 year of age.[3]
- 8% of RSV cases occur in individuals aged ≥65 years.[3]
Mortality Rate
The overall crude mortality rate due to RVS (cause of death unspecified) in the United States was 7.8 per 100,000 individuals. A breakdown of the mortality rate by age group revealed that the rate was highest among individuals aged 65 years or older, at 46.8 per 100,000. The mortality rate was also elevated among those aged 50-64 years, at 11.8 per 100,000. In contrast, the mortality rate was lower among individuals aged 1-4 years, at 1.1 per 100,000, and even lower among those aged one year or less, at 2.7 per 100,000. [4]
Seasonal Trends
RSV circulation in the United States (except Floria and Hawai) and similar climates typically starts in fall and peaks in winter:[5]
- Season onset ranged from mid-September to mid-November.
- Season peak ranged from late December to mid-February.
- Season offset ranged from mid-April to mid-May.
Prior to 2020, RSV seasonal patterns in the United States were consistent, but have been disrupted since the onset of the COVID-19 pandemic.[6]
References
- ↑ "www.cdc.gov" (PDF). Retrieved 2023-01-16.
- ↑ "RSV-NET Interactive Dashboard | CDC". Retrieved 2023-01-16.
- ↑ 3.0 3.1 Staadegaard L, Caini S, Wangchuk S, Thapa B, de Almeida WAF, de Carvalho FC; et al. (2021). "The Global Epidemiology of RSV in Community and Hospitalized Care: Findings From 15 Countries". Open Forum Infect Dis. 8 (7): ofab159. doi:10.1093/ofid/ofab159. PMC 8320297 Check
|pmc=value (help). PMID 34337092 Check|pmid=value (help). - ↑ Hansen CL, Chaves SS, Demont C, Viboud C (2022). "Mortality Associated With Influenza and Respiratory Syncytial Virus in the US, 1999-2018". JAMA Netw Open. 5 (2): e220527. doi:10.1001/jamanetworkopen.2022.0527. PMC 8886548 Check
|pmc=value (help). PMID 35226079 Check|pmid=value (help). - ↑ "Respiratory Syncytial Virus Seasonality — United States, 2014–2017 | MMWR". Retrieved 2023-01-16.
- ↑ "Changes in Influenza and Other Respiratory Virus Activity During the COVID-19 Pandemic — United States, 2020–2021 | MMWR". Retrieved 2023-01-16.