Intraductal papilloma

Intraductal papilloma
Classification and external resources
Histopathology of intraductal papilloma of the breast by excisional biopsy. Immunostaining for p63 protein.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Intraductal papillomas of the breast are relatively common benign lesions with an incidence of approximately 2-3% in humans. They are the most common cause of bloody nipple discharge in women age 20-40 and generally do not show up on mammography due to their small size, so the next step in treatment would be a galactogram to guide the subsequent biopsy.The masses are often too small to be palpated or felt. A galactogram is therefore necessary to rule out the lesion. Excision is sometimes performed as the method of treatment.

Additional Images

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  Histopathology of intraductal papilloma of the breast by excisional biopsy. Hematoxylin and eosin stain.
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  Histopathology of intraductal papilloma of the breast by excisional biopsy. Immunostaining for alpha-smooth muscle actin.