Liposarcoma risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Common risk factors in the development of liposarcoma are:^[1]^[1]

Radiation
- Risk is associated with adjuvant therapy of radiation for breast carcinoma.
- Risk increases with dose and a dose of 50 GY or more of radiation has been recorded with increased risk of sarcoma.
- The mean period between exposure to radiation and tumor diagnosis is 10 years.

Immunodeficiency
- Regional acquired immunodeficiency is sometimes associated with liposarcoma.