Mediastinal mass causes
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Mediastinal mass Microchapters |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]
Overview
The mediastinum is a non-delineated group of structures in the thorax (chest), surrounded by loose connective tissue. It is the central compartment of the thoracic cavity. It contains the heart, the great vessels of the heart, esophagus, trachea, thymus, and lymph nodes of the central chest. A wide variety of diseases involving these organs can present as a mediastinal mass or widening of the mediastinum on imaging studies.
Causes
Following can appear as a mediastinal mass on imaging studies:
Disease | |
---|---|
Cardiovascular causes | |
Gastrointestinal causes | |
Pulmonary causes | |
CNS diseases | |
Thyroid diseases | |
Mediastinal tumors | |
Cystic mass | |
Other |
Causes by Organ System
Cardiovascular | |
Chemical / poisoning |
|
Dermatologic |
|
Drug Side Effect |
|
Ear Nose Throat |
|
Endocrine | |
Environmental |
|
Gastroenterologic | |
Genetic | No underlying causes |
Hematologic | |
Iatrogenic | |
Infectious Disease | |
Musculoskeletal / Ortho | No underlying causes |
Neurologic | |
Nutritional / Metabolic |
|
Obstetric/Gynecologic |
|
Oncologic | |
Opthalmologic |
|
Overdose / Toxicity |
|
Psychiatric |
|
Pulmonary |
|
Renal / Electrolyte |
|
Rheum / Immune / Allergy | |
Sexual |
|
Trauma |
|
Urologic |
|
Miscellaneous |
|
Causes in Alphabetical Order
- Anthrax
- Aortic dissection
- Bronchogenic cyst
- Churg-Strauss syndrome
- Esophageal achalasia
- Esophageal cancer
- Esophageal rupture
- Goitre
- Hiatus hernia
- Hilar lymphadenopathy
- Lymphoma
- Mediastinal germ cell tumor
- Mediastinitis
- Neurilemmoma
- Non-Hodgkin lymphoma
- Partial anomalous pulmonary venous connection
- Pericardial effusion
- Pneumomediastinum
- Sarcoidosis
- Superior vena cava obstruction
- Teratoma
- Thymoma
- Thyroid cancer
- Tuberculosis
References
- ↑ Cohen R, Mena D, Carbajal-Mendoza R, Matos N, Karki N (2008). "Superior vena cava syndrome: A medical emergency?". Int. J. Angiol. 17 (1): 43–6. PMID 22477372.
- ↑ Sears EH, Aliotta JM, Klinger JR (2012). "Partial anomalous pulmonary venous return presenting with adult-onset pulmonary hypertension". Pulm Circ. 2 (2): 250–5. doi:10.4103/2045-8932.97637. PMC 3401879. PMID 22837866.
- ↑ Broy C, Bennett S (June 2008). "Partial anomalous pulmonary venous return". Mil Med. 173 (6): 523–4. PMID 18595412.
- ↑ Vanneman MW, Fikry K, Quraishi SA, Schoenfeld W (August 2015). "A Young Man with a Mediastinal Mass and Sudden Cardiac Arrest". Ann Am Thorac Soc. 12 (8): 1235–9. doi:10.1513/AnnalsATS.201504-212CC. PMID 26317273.
- ↑ Salem K, Mulji A, Lonn E (November 1999). "Echocardiographically guided pericardiocentesis - the gold standard for the management of pericardial effusion and cardiac tamponade". Can J Cardiol. 15 (11): 1251–5. PMID 10579740.
- ↑ Brooke V, Goswami S, Mohanty A, Kasi PM (2012). "Aortic dissection and renal failure in a patient with severe hypothyroidism". Case Rep Med. 2012: 842562. doi:10.1155/2012/842562. PMC 3399550. PMID 22829842.
- ↑ "Classification of diabetic retinopathy from fluorescein angiograms. ETDRS report number 11. Early Treatment Diabetic Retinopathy Study Research Group". Ophthalmology. 98 (5 Suppl): 807–22. 1991. PMID 2062514.
- ↑ Gockel I, Müller M, Schumacher J (2012). "Achalasia--a disease of unknown cause that is often diagnosed too late". Dtsch Arztebl Int. 109 (12): 209–14. doi:10.3238/arztebl.2012.0209. PMC 3329145. PMID 22532812.
- ↑ Ghoshal UC, Daschakraborty SB, Singh R (2012). "Pathogenesis of achalasia cardia". World J. Gastroenterol. 18 (24): 3050–7. doi:10.3748/wjg.v18.i24.3050. PMC 3386318. PMID 22791940.
- ↑ Nakajima S, Hattori T. Oesophageal adenocarcinoma or gastric cancer with or without eradication of Helicobacter pylori infection in chronic atrophic gastritis patients: a hypothetical opinion from a systematic review. Aliment Pharmacol Ther. 2004 Jul;20 Suppl 1:54-61. PMID 15298606
- ↑ NCI Prevention: Dietary Factors, based on Chainani-Wu N. Diet and oral, pharyngeal, and esophageal cancer. Nutr Cancer 2002;44:104-26. PMID 12734057.
- ↑ McGovern M, Egerton MJ (1991). "Spontaneous perforation of the cervical oesophagus". Med. J. Aust. 154 (4): 277–8. PMID 1994204.
- ↑ Wilson RF, Sarver EJ, Arbulu A, Sukhnandan R (1971). "Spontaneous perforation of the esophagus". Ann. Thorac. Surg. 12 (3): 291–6. PMID 5112482.
- ↑
- ↑ Chang P, Friedenberg F (2014). "Obesity and GERD". Gastroenterol Clin North Am. 43 (1): 161–73. doi:10.1016/j.gtc.2013.11.009. PMC 3920303. PMID 24503366.
- ↑ Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A (2014). "Peripheral lymphadenopathy: approach and diagnostic tools". Iran J Med Sci. 39 (2 Suppl): 158–70. PMC 3993046. PMID 24753638.
- ↑ Lymph node enlargment. Radiopedia. http://radiopaedia.org/articles/lymph-node-enlargement Accessed on May 9, 2016
- ↑ Chiu CY, Wong KS, Yao TC, Huang JL (March 2005). "Asthmatic versus non-asthmatic spontaneous pneumomediastinum in children". Asian Pac. J. Allergy Immunol. 23 (1): 19–22. PMID 15997870.
- ↑ Iyer VN, Joshi AY, Ryu JH (May 2009). "Spontaneous pneumomediastinum: analysis of 62 consecutive adult patients". Mayo Clin. Proc. 84 (5): 417–21. doi:10.1016/S0025-6196(11)60560-0. PMC 2676124. PMID 19411438.
- ↑ Dionísio, Patrícia; Martins, Luís; Moreira, Susana; Manique, Alda; Macedo, Rita; Caeiro, Fátima; Boal, Luísa; Bárbara, Cristina (2017). "Spontaneous pneumomediastinum: experience in 18 patients during the last 12 years". Jornal Brasileiro de Pneumologia. 43 (2): 101–105. doi:10.1590/s1806-37562016000000052. ISSN 1806-3756.
- ↑ Teirstein AS, Judson MA, Baughman RP, et al: The spectrum of biopsy sites for the diagnosis of sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 22(2):139 146, 2005.
- ↑ Judson MA, Boan AD, Lackland DT: The clinical course of sarcoidosis: presentation, diagnosis, and treatment in a large white and black cohort in the United States. Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 2012, 29(2):119-127.
- ↑ "Symptoms | Anthrax | CDC".
- ↑ "Anthrax in Humans and Animals" (PDF).
- ↑ "Tuberculosis Fact Sheet".
- ↑ Griffith D, Kerr C (1996). "Tuberculosis: disease of the past, disease of the present". J Perianesth Nurs. 11 (4): 240–5. PMID 8964016.
- ↑ 27.00 27.01 27.02 27.03 27.04 27.05 27.06 27.07 27.08 27.09 27.10 27.11 27.12 Juanpere S, Cañete N, Ortuño P, Martínez S, Sanchez G, Bernado L (February 2013). "A diagnostic approach to the mediastinal masses". Insights Imaging. 4 (1): 29–52. doi:10.1007/s13244-012-0201-0. PMID 23225215.
- ↑ "What is Spina Bifida | CDC".
- ↑ Mitchell LE, Adzick NS, Melchionne J, Pasquariello PS, Sutton LN, Whitehead AS (2004). "Spina bifida". Lancet. 364 (9448): 1885–95. doi:10.1016/S0140-6736(04)17445-X. PMID 15555669.
- ↑ "Schwannoma | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program".
- ↑ "Benign thyroid enlargement (non-toxic multinodular goiter): Overview".
- ↑ Sandlund JT (2015). "Non-Hodgkin Lymphoma in Children". Curr Hematol Malig Rep. 10 (3): 237–43. doi:10.1007/s11899-015-0277-y. PMID 26174528.
- ↑ Armitage JO, Gascoyne RD, Lunning MA, Cavalli F (2017). "Non-Hodgkin lymphoma". Lancet. 390 (10091): 298–310. doi:10.1016/S0140-6736(16)32407-2. PMID 28153383.
- ↑ J. J. Goedert, T. R. Cote, P. Virgo, S. M. Scoppa, D. W. Kingma, M. H. Gail, E. S. Jaffe & R. J. Biggar (1998). "Spectrum of AIDS-associated malignant disorders". Lancet (London, England). 351 (9119): 1833–1839. PMID 9652666. Unknown parameter
|month=
ignored (help) - ↑ M. Tinguely, R. Vonlanthen, E. Muller, C. C. Dommann-Scherrer, J. Schneider, J. A. Laissue & B. Borisch (1998). "Hodgkin's disease-like lymphoproliferative disorders in patients with different underlying immunodeficiency states". Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 11 (4): 307–312. PMID 9578079. Unknown parameter
|month=
ignored (help) - ↑ No TH, Seol SH, Seo GW, Kim DI, Yang SY, Jeong CH, Hwang YH, Kim JY (September 2015). "Benign Mature Teratoma in Anterior Mediastinum". J Clin Med Res. 7 (9): 726–8. doi:10.14740/jocmr2270w. PMC 4522994. PMID 26251691.
- ↑ Molinari F, Bankier AA, Eisenberg RL (November 2011). "Fat-containing lesions in adult thoracic imaging". AJR Am J Roentgenol. 197 (5): W795–813. doi:10.2214/AJR.11.6932. PMID 22021525.
- ↑ Carr RF, Ochs RH, Ritter DA, Kenny JD, Fridey JL, Ming PM (June 1986). "Fetal cystic hygroma and Turner's syndrome". Am. J. Dis. Child. 140 (6): 580–3. PMID 3706240.
- ↑ Setty, HAN; Hegde, KKS; Narvekar, VN (2005). "Neurenteric cyst of the posterior mediastinum". Australasian Radiology. 49 (2): 151–153. doi:10.1111/j.1440-1673.2005.01360.x. ISSN 0004-8461.
- ↑ Elta, Grace H; Enestvedt, Brintha K; Sauer, Bryan G; Marie Lennon, Anne (2018). "ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts". The American Journal of Gastroenterology. 113 (4): 464–479. doi:10.1038/ajg.2018.14. ISSN 0002-9270.
- ↑ Kondov, Goran; Kondov, Borislav; Srceva, Marija Jovanovska; Damjanovski, Goge; Ferati, Imran; Karapetrov, Ivan; Topuzovska, Irena Kondova; Tanevska, Nikolina; Kokareva, Anita (2017). "Giant Mediastinal Thymic Cyst". PRILOZI. 38 (2): 139–145. doi:10.1515/prilozi-2017-0032. ISSN 1857-8985.
- ↑ Symptoms of mediastinitis. Right Diagnosis (2015). http://www.rightdiagnosis.com/m/mediastinitis/symptoms.htm Accessed on September 28, 2015
- ↑ Mediastinitis: parotid abscess complication. Brazilian Journal of Otorhinolaryngology (2013). http://www.scielo.br/scielo.php?pid=S1808-86942014000300268&script=sci_arttext Accessed on September 28, 2015
- ↑ Silva CI, Müller NL, Fujimoto K, Johkoh T, Ajzen SA, Churg A (May 2005). "Churg-Strauss syndrome: high resolution CT and pathologic findings". J Thorac Imaging. 20 (2): 74–80. PMID 15818205.
- ↑ Feng RE, Xu WB, Shi JH, Mahmoudi A, Mu WB, Zheng WJ, Zhu YJ, Liu HR (March 2011). "Pathological and high resolution CT findings in Churg-Strauss syndrome". Chin. Med. Sci. J. 26 (1): 1–8. PMID 21496416.