Microangiopathic hemolytic anemia history and symptoms
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Overview
The patients have a wide spectrum of clinical picture ranging from asymptomatic to anemia, thrombocytopenia, fever, altered mental status and impaired renal function[1]. Some patients may also present with abdominal or cardiac symptoms[2].
History and Symptoms
Common Symptoms
Common symptoms of microangiopathic hemolytic anemia include[2][3]:
- Pallor
- Yellowing of sclera and skin
- Dark colored urine due to raised level of urobilinogen and unconjugated bilirubin
- Breathlessness
- Easy fatigability
- Petechia
- Purpura
- Epistaxis
- Bleeding from mucous membranes
- Fever
- Altered mental status
- Seizures
- Stroke
- Dizziness
- Slurred speech
- Transient ischemic attacks
- Renal failure
- Oliguria
Less Common Symptoms
Less common symptoms of microangiopathic hemolytic anemia include:
References
- ↑ George JN, Nester CM (2014). "Syndromes of thrombotic microangiopathy". N Engl J Med. 371 (7): 654–66. doi:10.1056/NEJMra1312353. PMID 25119611.
- ↑ 2.0 2.1 Kottke-Marchant K (2017). "Diagnostic approach to microangiopathic hemolytic disorders". Int J Lab Hematol. 39 Suppl 1: 69–75. doi:10.1111/ijlh.12671. PMID 28447417.
- ↑ "Correction to Lancet Infectious Diseases 2020; published online April 29. https://doi.org/10.1016/ S1473-3099(20)30064-5". Lancet Infect Dis. 20 (7): e148. 2020. doi:10.1016/S1473-3099(20)30370-4. PMID 32595044 Check
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