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Middle East Respiratory Syndrome Coronavirus Infection Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The symptoms of the middle east respiratory syndrome coronavirus infection include fever, cough, shortness of breath and gatsrointestinal symptoms.

History and Symptoms

Symptom Percentage
Fever
   Fever with chills or rigors
98%
   87%
Cough
   Dry
   Productive
83%
   47%
   36%
Hemoptysis 17%
Shortnes of breath 72%
Chest Pain 15%
Sore throat 21%
Runny Nose 4%
Abdominal Pain 17%
Nausea 21%
Vomiting 21%
Diarrhoea 26%
Myalgia 32%
Headache 13%

Suspect MERS-CoV infection in case of:

  • Fever (≥38°C, 100.4°F) and pneumonia or acute respiratory distress syndrome (based on clinical or radiological evidence);

AND EITHER

  • History of travel from countries in or near the Arabian Peninsula1 within 14 days before symptom onset;

OR

  • Close contact2 with a symptomatic traveler who developed fever and acute respiratory illness (not necessarily pneumonia) within 14 days after traveling from countries in or near the Arabian Peninsula;

OR

  • Is a member of a cluster of patients with severe acute respiratory illness (e.g. fever and pneumonia requiring hospitalization) of unknown etiology in which MERS-CoV is being evaluated, in consultation with state and local health departments.

Symptoms

All but two patients (96%) had one or more chronic medical conditions, including diabetes (68%), hypertension (34%), heart disease (28%), and kidney disease (49%). Thirty-four (72%) had more than one chronic condition. In a retrospective study on 47 patients with MERS-CoV infection, 42 (89%) needed intensive care and 34 (72%) had mechanical ventilation.[1]

References

  1. Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A; et al. (2013). "Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study". Lancet Infect Dis. 13 (9): 752–61. doi:10.1016/S1473-3099(13)70204-4. PMID 23891402.

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