Sandbox:epidem
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Neuroblastoma is the most common extracranial solid cancer in childhood and the most common cancer in infancy.[1] The overall incidence rate of neuroblastoma is approximately 4.9 per 1,000,000 individuals in the United States.[2] The incidence of neuroblastoma decreases with age; the highest incidence is in the first year of life. Males are slightly more commonly affected with neuroblastoma than females. The male to female ratio is approximately 1.12 to 1. Neuroblastoma usually affects individuals of the Caucasian race. African American, Native Indian and Asian individuals are less likely to develop neuroblastoma.
Epidemiology and Demographics
Prevalence
- Neuroblastoma is the most common extracranial solid cancer in childhood and the most common cancer in infancy.[1]
Incidence
- The overall incidence rate of neuroblastoma is approximately 4.9 per 1,000,000 individuals in the United States.[2]
Age
- The incidence of neuroblastoma decreases with age; the highest incidence is in the first year of life.[2]
- The incidence of neuroblastoma according to specific age groups is approximately:
- 25.3 per 1,000,000 individuals aged between (0-4) years
- 2.3 per 1,000,000 individuals aged between (5-9) years
- 0.7 per 1,000,000 individuals aged between (10-14) years
- 0.2 per 1,000,000 individuals aged between (20-24) years
- 0.3 per 1,000,000 individuals aged between (25-29) years
Gender
- Males are slightly more commonly affected with neuroblastoma than females. The male to female ratio is approximately 1.12 to 1.[2]
- The incidence rate of neuroblastoma among males is approximately 5.1 per 1,000,000 individuals in the United States.
- The incidence rate of neuroblastoma among females is approximately 4.6 per 1,000,000 individuals in the United States.
Race
- Neuroblastoma usually affects individuals of the Caucasian race. African American, Native Indian and Asian individuals are less likely to develop neuroblastoma.[2]
- The incidence rate of neuroblastoma among Caucasians is approximately 5.1 per 1,000,000 individuals in the United States.
- The incidence rate of neuroblastoma among African Americans is approximately 4.1 per 1,000,000 individuals in the United States.
- The overall incidence rate of neuroblastoma among Native Indians and Asians is approximately 3.8 per 1,000,000 individuals in the United States.