Wilson's disease MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [3]

Overview

There are no specific MRI findings associated with Wilson's disease especially in cases who present with only hepatic manifestations. However, it may show abnormalities in the basal ganglia in the patients who presented with neuropsychiatric manifestations. MRI of the liver can aid in evaluation of copper deposition.

MRI

  • There are no specific MRI findings associated with Wilson's disease especially who present with only hepatic manifestations.
  • In patients who presented with neuropsychiatric manifestations, brain MRI may show structural abnormalities in the basal ganglia.[1]

Source: Case courtesy of A.Prof Frank Gaillard, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/3872">rID: 3872</a>

  • MRI of the liver can aid in evaluation of copper deposition.

References

  1. Kim TJ, Kim IO, Kim WS, Cheon JE, Moon SG, Kwon JW; et al. (2006). "MR imaging of the brain in Wilson disease of childhood: findings before and after treatment with clinical correlation". AJNR Am J Neuroradiol. 27 (6): 1373–8. PMID 16775300.