Differentiating Cretinism from other diseases: Difference between revisions
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!Disease | ! style="background: #4479BA; text-align: center;" |{{fontcolor|#FFF|Disease}} | ||
!Prominent clinical features | ! style="background: #4479BA; text-align: center;" |{{fontcolor|#FFF|Prominent clinical features}} | ||
!Radiological findings | ! style="background: #4479BA; text-align: center;" |{{fontcolor|#FFF|Radiological findings}} | ||
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|Cretinism (Congenital hypothyroidism) | | style="background: #DCDCDC; text-align: center;" |Cretinism (Congenital hypothyroidism) | ||
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*Most infants are born [[asymptomatic]].<ref name="pmid2295961">{{cite journal |vauthors= |title=Elementary school performance of children with congenital hypothyroidism. New England Congenital Hypothyroidism Collaborative |journal=J. Pediatr. |volume=116 |issue=1 |pages=27–32 |year=1990 |pmid=2295961 |doi= |url=}}</ref> | *Most infants are born [[asymptomatic]].<ref name="pmid2295961">{{cite journal |vauthors= |title=Elementary school performance of children with congenital hypothyroidism. New England Congenital Hypothyroidism Collaborative |journal=J. Pediatr. |volume=116 |issue=1 |pages=27–32 |year=1990 |pmid=2295961 |doi= |url=}}</ref> | ||
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|[[Meconium plug syndrome]] | | style="background: #DCDCDC; text-align: center;" |[[Meconium plug syndrome]] | ||
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* Transient [[intestinal obstruction]] for 1-2 days after birth. | * Transient [[intestinal obstruction]] for 1-2 days after birth. | ||
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|[[Image:Meconium-plug-syndrome - Case courtesy of Radswiki, Radiopaedia.org, rID 11606.jpg|center|300px|thumb|Abdominal x-ray with contrast showing inspissated meconium in the intestine, proximal to the colon - Case courtesy of Radswiki, Radiopaedia.org, rID 11606]] | |[[Image:Meconium-plug-syndrome - Case courtesy of Radswiki, Radiopaedia.org, rID 11606.jpg|center|300px|thumb|Abdominal x-ray with contrast showing inspissated meconium in the intestine, proximal to the colon - Case courtesy of Radswiki, Radiopaedia.org, rID 11606]] | ||
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|[[Small left colon syndrome]] | | style="background: #DCDCDC; text-align: center;" |[[Small left colon syndrome]] | ||
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* Reduced caliber of the [[colon]] starting from [[splenic flexure]] and going down, causing [[intestinal obstruction]]. | * Reduced caliber of the [[colon]] starting from [[splenic flexure]] and going down, causing [[intestinal obstruction]]. | ||
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|[[Image:Small-left-colon-syndrome-1 - Case courtesy of Dr Eric F Greif, Radiopaedia.org, rID 30024.jpg|center|300px|thumb|Abdominal x-ray with contrast, shows decreased caliber of the descending and sigmoid colon, loss of haustration along with filling defects corresponding to retained feces - Case courtesy of Dr Eric F Greif, Radiopaedia.org, rID 30024]] | |[[Image:Small-left-colon-syndrome-1 - Case courtesy of Dr Eric F Greif, Radiopaedia.org, rID 30024.jpg|center|300px|thumb|Abdominal x-ray with contrast, shows decreased caliber of the descending and sigmoid colon, loss of haustration along with filling defects corresponding to retained feces - Case courtesy of Dr Eric F Greif, Radiopaedia.org, rID 30024]] | ||
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|[[Intestinal atresia|Distal small intestine/colon atresia]] | | style="background: #DCDCDC; text-align: center;" |[[Intestinal atresia|Distal small intestine/colon atresia]] | ||
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* Failure to pass [[meconium]] due to failure of [[intestine]] recanalization. | * Failure to pass [[meconium]] due to failure of [[intestine]] recanalization. | ||
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|[[Image:Small-bowel-atresia - Case courtesy of A.Prof Frank Gaillard, Radiopaedia.org, rID 5959.jpg|center|300px|thumb|Normal appearing colon that is small and unused. Contrast fills the whole colon and passes to the ileum - Case courtesy of A.Prof Frank Gaillard, Radiopaedia.org, rID 5959]] | |[[Image:Small-bowel-atresia - Case courtesy of A.Prof Frank Gaillard, Radiopaedia.org, rID 5959.jpg|center|300px|thumb|Normal appearing colon that is small and unused. Contrast fills the whole colon and passes to the ileum - Case courtesy of A.Prof Frank Gaillard, Radiopaedia.org, rID 5959]] | ||
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|[[Meconium ileus]] | | style="background: #DCDCDC; text-align: center;" |[[Meconium ileus]] | ||
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* [[Intestinal obstruction]] due to [[inspissation]] of [[meconium]] in the [[Ileum|distal ileum]]. | * [[Intestinal obstruction]] due to [[inspissation]] of [[meconium]] in the [[Ileum|distal ileum]]. | ||
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{{WS}} | {{WS}} | ||
{{WH}} | {{WH}} | ||
[[Category:Medicine]] | |||
[[Category:Endocrinology]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Pediatrics]] | |||
Latest revision as of 14:35, 30 October 2017
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Cretinism Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Differentiating Cretinism from other diseases On the Web |
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American Roentgen Ray Society Images of Differentiating Cretinism from other diseases |
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Risk calculators and risk factors for Differentiating Cretinism from other diseases |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Cretinism must be differentiated from other diseases that cause a failure to pass meconium or abdominal distension in infants, including meconium plug syndrome, small left colon syndrome, and Hirschsprung's disease.
Differentiating cretinism from other Diseases
Cretinism must be differentiated from other diseases that cause a failure to pass meconium or abdominal distension in infants, including meconium plug syndrome, small left colon syndrome, and Hirschsprung's disease.
| Disease | Prominent clinical features | Radiological findings |
|---|---|---|
| Cretinism (Congenital hypothyroidism) |
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| Meconium plug syndrome |
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| Small left colon syndrome |
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| Distal small intestine/colon atresia |
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| Meconium ileus |
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References
- ↑ "Elementary school performance of children with congenital hypothyroidism. New England Congenital Hypothyroidism Collaborative". J. Pediatr. 116 (1): 27–32. 1990. PMID 2295961.
- ↑ Keckler SJ, St Peter SD, Spilde TL, Tsao K, Ostlie DJ, Holcomb GW, Snyder CL (2008). "Current significance of meconium plug syndrome". J. Pediatr. Surg. 43 (5): 896–8. doi:10.1016/j.jpedsurg.2007.12.035. PMC 3086204. PMID 18485962.
- ↑ Berdon WE, Slovis TL, Campbell JB, Baker DH, Haller JO (1977). "Neonatal small left colon syndrome: its relationship with aganglionosis and meconium plug syndrome". Radiology. 125 (2): 457–62. doi:10.1148/125.2.457. PMID 910057.
- ↑ Spitz L (2006). "Observations on the origin of congenital intestinal atresia". S. Afr. Med. J. 96 (9 Pt 2): 864. PMID 17077911.
- ↑ HOLSCLAW DS, ECKSTEIN HB, NIXON HH (1965). "MECONIUM ILEUS. A 20-YEAR REVIEW OF 109 CASES". Am. J. Dis. Child. 109: 101–13. PMID 14237408.