Esthesioneuroblastoma classification: Difference between revisions
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==Overview== | ==Overview== | ||
Based on the duration of symptoms, esthesioneuroblastoma may be classified into two subtypes: [[neuroblastoma]] proper and neuroendocrine carcinomas.<ref name="pmid7483011">{{cite journal| author=Min KW| title=Usefulness of electron microscopy in the diagnosis of "small" round cell tumors of the sinonasal region. | journal=Ultrastruct Pathol | year= 1995 | volume= 19 | issue= 5 | pages= 347-63 | pmid=7483011 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7483011 }} </ref> | |||
==Classification== | ==Classification== | ||
* | *Neuroblastoma proper | ||
** | **[[Neuroblastoma]] proper has a histologic presentation similar to that of peripheral neuroblastomas of childhood. | ||
** | **Esthesioneuroblastoma is composed of sheets of poorly demarcated groups of cells separated by fine connective tissue trabeculae. | ||
**The cells are small and typically show no mitotic activity | **The cells are small and typically show no mitotic activity between the cells. | ||
**Rosettes of the Homer-Wright type are present. | **Rosettes of the Homer-Wright type are present. | ||
**On electronic microscopy, there is the presence of a dendritic cytoplasmic process with accumulations of small core granules within the process. | **On electronic microscopy, there is the presence of a dendritic cytoplasmic process with accumulations of small core granules within the process. | ||
**Neuroblastomas proper contain fibrillary material | **Neuroblastomas proper contain fibrillary material. | ||
*Neuroendocrine carcinomas | *Neuroendocrine carcinomas | ||
**Neuroendocrine | **Neuroendocrine carcinoma is admixture with glands. | ||
** | **A neurofibrillary component is absent and the growth pattern is that of solid nests without rosettes. | ||
**Dense core granules similar to those of | **Dense core granules similar to those of neuroblastomas are present in the cytoplasm and cytoplasmic extensions. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
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[[Category:neurology]] | [[Category:neurology]] | ||
[[Category:Rhinology]] | [[Category:Rhinology]] | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Neurology]] | |||
[[Category:Neurosurgery]] | |||
Latest revision as of 22:23, 26 November 2017
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Esthesioneuroblastoma Microchapters | |
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Esthesioneuroblastoma classification On the Web | |
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American Roentgen Ray Society Images of Esthesioneuroblastoma classification | |
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Risk calculators and risk factors for Esthesioneuroblastoma classification | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Based on the duration of symptoms, esthesioneuroblastoma may be classified into two subtypes: neuroblastoma proper and neuroendocrine carcinomas.[1]
Classification
- Neuroblastoma proper
- Neuroblastoma proper has a histologic presentation similar to that of peripheral neuroblastomas of childhood.
- Esthesioneuroblastoma is composed of sheets of poorly demarcated groups of cells separated by fine connective tissue trabeculae.
- The cells are small and typically show no mitotic activity between the cells.
- Rosettes of the Homer-Wright type are present.
- On electronic microscopy, there is the presence of a dendritic cytoplasmic process with accumulations of small core granules within the process.
- Neuroblastomas proper contain fibrillary material.
- Neuroendocrine carcinomas
- Neuroendocrine carcinoma is admixture with glands.
- A neurofibrillary component is absent and the growth pattern is that of solid nests without rosettes.
- Dense core granules similar to those of neuroblastomas are present in the cytoplasm and cytoplasmic extensions.
References
- ↑ Min KW (1995). "Usefulness of electron microscopy in the diagnosis of "small" round cell tumors of the sinonasal region". Ultrastruct Pathol. 19 (5): 347–63. PMID 7483011.