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'''Glutamate [NMDA] receptor subunit 3B''' is a [[protein]] that in humans is encoded by the ''GRIN3B'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=116444| accessdate = }}</ref> | |||
}} | |||
'''Glutamate receptor | |||
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==See also== | |||
* [[NMDA receptor]] | |||
==References== | ==References== | ||
{{reflist | {{reflist}} | ||
==Further reading== | ==Further reading== | ||
{{refbegin | 2}} | {{refbegin | 2}} | ||
{{PBB_Further_reading | {{PBB_Further_reading | ||
| citations = | | citations = | ||
*{{cite journal | *{{cite journal |vauthors=Schröder HC, Perovic S, Kavsan V, etal |title=Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death. |journal=Neurotoxicology |volume=19 |issue= 4–5 |pages= 683–8 |year= 1998 |pmid= 9745929 |doi= }} | ||
*{{cite journal | | *{{cite journal |vauthors=Kornau HC, Schenker LT, Kennedy MB, Seeburg PH|authorlink3=Mary B. Kennedy |title=Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95 |journal=Science |volume=269 |issue= 5231 |pages= 1737–40 |year= 1995 |pmid= 7569905 |doi=10.1126/science.7569905 }} | ||
*{{cite journal | *{{cite journal |vauthors=Magnuson DS, Knudsen BE, Geiger JD, etal |title=Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity |journal=Ann. Neurol. |volume=37 |issue= 3 |pages= 373–80 |year= 1995 |pmid= 7695237 |doi= 10.1002/ana.410370314 }} | ||
*{{cite journal | *{{cite journal |vauthors=Lannuzel A, Lledo PM, Lamghitnia HO, etal |title=HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons |journal=Eur. J. Neurosci. |volume=7 |issue= 11 |pages= 2285–93 |year= 1996 |pmid= 8563977 |doi=10.1111/j.1460-9568.1995.tb00649.x }} | ||
*{{cite journal | *{{cite journal |vauthors=Corasaniti MT, Melino G, Navarra M, etal |title=Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase |journal=Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration |volume=4 |issue= 3 |pages= 315–21 |year= 1996 |pmid= 8581564 |doi= 10.1016/1055-8330(95)90021-7}} | ||
*{{cite journal | | *{{cite journal |vauthors=Pittaluga A, Pattarini R, Severi P, Raiteri M |title=Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120 |journal=AIDS |volume=10 |issue= 5 |pages= 463–8 |year= 1996 |pmid= 8724036 |doi=10.1097/00002030-199605000-00003 }} | ||
*{{cite journal | *{{cite journal |vauthors=Wu P, Price P, Du B, etal |title=Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons |journal=NeuroReport |volume=7 |issue= 5 |pages= 1045–9 |year= 1996 |pmid= 8804048 |doi=10.1097/00001756-199604100-00018 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Bennett BA, Rusyniak DE, Hollingsworth CK |title=HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures |journal=Brain Res. |volume=705 |issue= 1–2 |pages= 168–76 |year= 1996 |pmid= 8821747 |doi=10.1016/0006-8993(95)01166-8 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Toggas SM, Masliah E, Mucke L |title=Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine |journal=Brain Res. |volume=706 |issue= 2 |pages= 303–7 |year= 1996 |pmid= 8822372 |doi=10.1016/0006-8993(95)01197-8 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Dreyer EB, Lipton SA |title=The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid |journal=Eur. J. Neurosci. |volume=7 |issue= 12 |pages= 2502–7 |year= 1996 |pmid= 8845955 |doi=10.1111/j.1460-9568.1995.tb01048.x }} | ||
*{{cite journal | | *{{cite journal |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }} | ||
*{{cite journal | *{{cite journal |vauthors=Raber J, Toggas SM, Lee S, etal |title=Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase |journal=Virology |volume=226 |issue= 2 |pages= 362–73 |year= 1997 |pmid= 8955056 |doi= 10.1006/viro.1996.0664 }} | ||
*{{cite journal | *{{cite journal |vauthors=New DR, Maggirwar SB, Epstein LG, etal |title=HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism |journal=J. Biol. Chem. |volume=273 |issue= 28 |pages= 17852–8 |year= 1998 |pmid= 9651389 |doi=10.1074/jbc.273.28.17852 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Wang P, Barks JD, Silverstein FS |title=Tat, a human immunodeficiency virus-1-derived protein, augments excitotoxic hippocampal injury in neonatal rats |journal=Neuroscience |volume=88 |issue= 2 |pages= 585–97 |year= 1999 |pmid= 10197777 |doi=10.1016/S0306-4522(98)00242-5 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Howard SA, Nakayama AY, Brooke SM, Sapolsky RM |title=Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures |journal=Exp. Neurol. |volume=158 |issue= 1 |pages= 164–70 |year= 1999 |pmid= 10448428 |doi= 10.1006/exnr.1999.7080 }} | ||
*{{cite journal | *{{cite journal |vauthors=Xin KQ, Hamajima K, Hattori S, etal |title=Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system |journal=AIDS Res. Hum. Retroviruses |volume=15 |issue= 16 |pages= 1461–7 |year= 1999 |pmid= 10555109 |doi= 10.1089/088922299309973 }} | ||
*{{cite journal | *{{cite journal |vauthors=Haughey NJ, Nath A, Mattson MP, etal |title=HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity |journal=J. Neurochem. |volume=78 |issue= 3 |pages= 457–67 |year= 2001 |pmid= 11483648 |doi=10.1046/j.1471-4159.2001.00396.x }} | ||
*{{cite journal | *{{cite journal |vauthors=Bonavia R, Bajetto A, Barbero S, etal |title=HIV-1 Tat causes apoptotic death and calcium homeostasis alterations in rat neurons |journal=Biochem. Biophys. Res. Commun. |volume=288 |issue= 2 |pages= 301–8 |year= 2001 |pmid= 11606043 |doi= 10.1006/bbrc.2001.5743 }} | ||
*{{cite journal | *{{cite journal |vauthors=Nishi M, Hinds H, Lu HP, etal |title=Motoneuron-specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner |journal=J. Neurosci. |volume=21 |issue= 23 |pages= RC185 |year= 2002 |pmid= 11717388 |doi= }} | ||
}} | }} | ||
{{refend}} | {{refend}} | ||
{{protein- | == External links == | ||
{{ | * {{MeshName|GRIN3B+protein,+human}} | ||
{{Ligand-gated ion channels}} | |||
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{{gene-19-stub}} | |||
[[Category:Ionotropic glutamate receptors]] |
Latest revision as of 20:34, 26 November 2017
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External IDs | GeneCards: [1] | ||||||
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Species | Human | Mouse | |||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a | |||||
Wikidata | |||||||
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Glutamate [NMDA] receptor subunit 3B is a protein that in humans is encoded by the GRIN3B gene.[1]
See also
References
Further reading
- Schröder HC, Perovic S, Kavsan V, et al. (1998). "Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death". Neurotoxicology. 19 (4–5): 683–8. PMID 9745929.
- Kornau HC, Schenker LT, Kennedy MB, Seeburg PH (1995). "Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95". Science. 269 (5231): 1737–40. doi:10.1126/science.7569905. PMID 7569905.
- Magnuson DS, Knudsen BE, Geiger JD, et al. (1995). "Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity". Ann. Neurol. 37 (3): 373–80. doi:10.1002/ana.410370314. PMID 7695237.
- Lannuzel A, Lledo PM, Lamghitnia HO, et al. (1996). "HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons". Eur. J. Neurosci. 7 (11): 2285–93. doi:10.1111/j.1460-9568.1995.tb00649.x. PMID 8563977.
- Corasaniti MT, Melino G, Navarra M, et al. (1996). "Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase". Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. 4 (3): 315–21. doi:10.1016/1055-8330(95)90021-7. PMID 8581564.
- Pittaluga A, Pattarini R, Severi P, Raiteri M (1996). "Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120". AIDS. 10 (5): 463–8. doi:10.1097/00002030-199605000-00003. PMID 8724036.
- Wu P, Price P, Du B, et al. (1996). "Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons". NeuroReport. 7 (5): 1045–9. doi:10.1097/00001756-199604100-00018. PMID 8804048.
- Bennett BA, Rusyniak DE, Hollingsworth CK (1996). "HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures". Brain Res. 705 (1–2): 168–76. doi:10.1016/0006-8993(95)01166-8. PMID 8821747.
- Toggas SM, Masliah E, Mucke L (1996). "Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine". Brain Res. 706 (2): 303–7. doi:10.1016/0006-8993(95)01197-8. PMID 8822372.
- Dreyer EB, Lipton SA (1996). "The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid". Eur. J. Neurosci. 7 (12): 2502–7. doi:10.1111/j.1460-9568.1995.tb01048.x. PMID 8845955.
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Raber J, Toggas SM, Lee S, et al. (1997). "Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase". Virology. 226 (2): 362–73. doi:10.1006/viro.1996.0664. PMID 8955056.
- New DR, Maggirwar SB, Epstein LG, et al. (1998). "HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism". J. Biol. Chem. 273 (28): 17852–8. doi:10.1074/jbc.273.28.17852. PMID 9651389.
- Wang P, Barks JD, Silverstein FS (1999). "Tat, a human immunodeficiency virus-1-derived protein, augments excitotoxic hippocampal injury in neonatal rats". Neuroscience. 88 (2): 585–97. doi:10.1016/S0306-4522(98)00242-5. PMID 10197777.
- Howard SA, Nakayama AY, Brooke SM, Sapolsky RM (1999). "Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures". Exp. Neurol. 158 (1): 164–70. doi:10.1006/exnr.1999.7080. PMID 10448428.
- Xin KQ, Hamajima K, Hattori S, et al. (1999). "Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system". AIDS Res. Hum. Retroviruses. 15 (16): 1461–7. doi:10.1089/088922299309973. PMID 10555109.
- Haughey NJ, Nath A, Mattson MP, et al. (2001). "HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity". J. Neurochem. 78 (3): 457–67. doi:10.1046/j.1471-4159.2001.00396.x. PMID 11483648.
- Bonavia R, Bajetto A, Barbero S, et al. (2001). "HIV-1 Tat causes apoptotic death and calcium homeostasis alterations in rat neurons". Biochem. Biophys. Res. Commun. 288 (2): 301–8. doi:10.1006/bbrc.2001.5743. PMID 11606043.
- Nishi M, Hinds H, Lu HP, et al. (2002). "Motoneuron-specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner". J. Neurosci. 21 (23): RC185. PMID 11717388.
External links
- GRIN3B+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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