Fat embolism syndrome laboratory findings: Difference between revisions
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{{CMG}} {{AE}} {{FT}} | {{CMG}} {{AE}} {{FT}} | ||
==Overview== | ==Overview== | ||
Laboratory tests are not done commonly to diagnose fat embolism. However, the most commonly seen findings are anemia, thrombocytopenia and lipidura. | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
=== Common Laboratory Findings: === | |||
The most commonly seen laboratory findings in fat embolism include: | |||
* [[Anemia]] | |||
* [[Thrombocytopenia]] | |||
* [[Lipiduria]] | |||
In some cases, fat embolism syndrome is associated with elevations in the following laboratory values:<ref name="KaoYeh2007">{{cite journal|last1=Kao|first1=Shang Jyh|last2=Yeh|first2=Diana Yu-Wung|last3=Chen|first3=Hsing I.|title=Clinical and pathological features of fat embolism with acute respiratory distress syndrome|journal=Clinical Science|volume=113|issue=6|year=2007|pages=279–285|issn=0143-5221|doi=10.1042/CS20070011}}</ref><ref name="pmid9108767">{{cite journal| author=Bulger EM, Smith DG, Maier RV, Jurkovich GJ| title=Fat embolism syndrome. A 10-year review. | journal=Arch Surg | year= 1997 | volume= 132 | issue= 4 | pages= 435-9 | pmid=9108767 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9108767 }} </ref> | |||
* Plasma PLA2 (phospholipase A2) | * Plasma PLA2 (phospholipase A2) | ||
* Nitrate/nitrite | * [[Nitrate]]/nitrite | ||
* Methylguanidine | * Methylguanidine | ||
* TNF-α (tumour necrosis factor-α) | * [[Tumor necrosis factor-alpha|TNF]]-α (tumour necrosis factor-α) | ||
* IL-1β (interleukin-1β) | * IL-1β ([[interleukin]]-1β) | ||
* IL-10 (interleukin-10) | * IL-10 ([[interleukin]]-10) | ||
* IL-6 (interleukin-6)<ref name="pmid23423626">{{cite journal| author=Prakash S, Sen RK, Tripathy SK, Sen IM, Sharma RR, Sharma S| title=Role of interleukin-6 as an early marker of fat embolism syndrome: a clinical study. | journal=Clin Orthop Relat Res | year= 2013 | volume= 471 | issue= 7 | pages= 2340-6 | pmid=23423626 | doi=10.1007/s11999-013-2869-y | pmc=3676609 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23423626 }} </ref> | * IL-6 ([[interleukin]]-6)<ref name="pmid23423626">{{cite journal| author=Prakash S, Sen RK, Tripathy SK, Sen IM, Sharma RR, Sharma S| title=Role of interleukin-6 as an early marker of fat embolism syndrome: a clinical study. | journal=Clin Orthop Relat Res | year= 2013 | volume= 471 | issue= 7 | pages= 2340-6 | pmid=23423626 | doi=10.1007/s11999-013-2869-y | pmc=3676609 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23423626 }} </ref> | ||
==References== | ==References== | ||
Latest revision as of 13:56, 6 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Feham Tariq, MD [2]
Overview
Laboratory tests are not done commonly to diagnose fat embolism. However, the most commonly seen findings are anemia, thrombocytopenia and lipidura.
Laboratory Findings
Common Laboratory Findings:
The most commonly seen laboratory findings in fat embolism include:
In some cases, fat embolism syndrome is associated with elevations in the following laboratory values:[1][2]
- Plasma PLA2 (phospholipase A2)
- Nitrate/nitrite
- Methylguanidine
- TNF-α (tumour necrosis factor-α)
- IL-1β (interleukin-1β)
- IL-10 (interleukin-10)
- IL-6 (interleukin-6)[3]
References
- ↑ Kao, Shang Jyh; Yeh, Diana Yu-Wung; Chen, Hsing I. (2007). "Clinical and pathological features of fat embolism with acute respiratory distress syndrome". Clinical Science. 113 (6): 279–285. doi:10.1042/CS20070011. ISSN 0143-5221.
- ↑ Bulger EM, Smith DG, Maier RV, Jurkovich GJ (1997). "Fat embolism syndrome. A 10-year review". Arch Surg. 132 (4): 435–9. PMID 9108767.
- ↑ Prakash S, Sen RK, Tripathy SK, Sen IM, Sharma RR, Sharma S (2013). "Role of interleukin-6 as an early marker of fat embolism syndrome: a clinical study". Clin Orthop Relat Res. 471 (7): 2340–6. doi:10.1007/s11999-013-2869-y. PMC 3676609. PMID 23423626.