Renal amyloidosis causes: Difference between revisions
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{{CMG}}; {{AE}} {{SHH}} | {{CMG}}; {{AE}} {{SHH}} | ||
==Overview== | ==Overview== | ||
The exact cause of renal amyloidiosis has not been identified. Most commonly causes of majority of the cases in renal amyloidosis idiopathic. Other causes include amyloidosis secondary to diseases such as [[tuberculosis]], [[Familial mediterranean fever|familial Mediterranean fever]], [[rheumatoid arthritis]], [[multiple myeloma]] or amyloidic mutations of [[transthyretin]] and [[fibrinogen]] protein. | |||
==Causes== | ==Causes== | ||
===Common Causes=== | ===Common Causes=== | ||
In renal amyloidosis, most common causes include:<ref name="pmid23704299">{{cite journal |vauthors=Said SM, Sethi S, Valeri AM, Leung N, Cornell LD, Fidler ME, Herrera Hernandez L, Vrana JA, Theis JD, Quint PS, Dogan A, Nasr SH |title=Renal amyloidosis: origin and clinicopathologic correlations of 474 recent cases |journal=Clin J Am Soc Nephrol |volume=8 |issue=9 |pages=1515–23 |date=September 2013 |pmid=23704299 |pmc=3805078 |doi=10.2215/CJN.10491012 |url=}}</ref> | |||
*[ | * Idiopathic ( Primary (AL) amyloidosis ) | ||
*[ | * Amyloidosis secondary to: | ||
*[ | ** [[Tuberculosis|TB]] | ||
[ | ** [[Familial mediterranean fever|Familial mediterranean fever (FMF)]] | ||
** [[Rheumatoid arthritis|Rheumatoid arthritis (RA)]] | |||
[ | ** [[Multiple myeloma]] | ||
===Less Common Causes=== | ===Less Common Causes=== | ||
In renal amyloidosis, less common causes include:<ref name="pmid24497558">{{cite journal |vauthors=Mahmood S, Palladini G, Sanchorawala V, Wechalekar A |title=Update on treatment of light chain amyloidosis |journal=Haematologica |volume=99 |issue=2 |pages=209–21 |date=February 2014 |pmid=24497558 |pmc=3912950 |doi=10.3324/haematol.2013.087619 |url=}}</ref> | |||
*[ | *.Hereditary amyloidosis due to amyloidogenic [[Mutation|mutations]]: | ||
*[ | ** [[Transthyretin|Transthyretin (TTR)]] (most common [[inherited]] [[mutation]]) | ||
*[ | ** [[Fibrinogen]] | ||
** [[Apolipoprotein A1]] | |||
** [[Apolipoprotein A2]] | |||
*[ | ** [[Lysozyme]] | ||
** [[Gelsolin]] [[Gene|genes]] | |||
==References== | ==References== | ||
Latest revision as of 18:51, 8 August 2018
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Renal amyloidosis Microchapters |
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Case Studies |
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Template:Renal amyloidosis On the Web |
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American Roentgen Ray Society Images of Renal amyloidosis causes |
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Risk calculators and risk factors for Renal amyloidosis causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
The exact cause of renal amyloidiosis has not been identified. Most commonly causes of majority of the cases in renal amyloidosis idiopathic. Other causes include amyloidosis secondary to diseases such as tuberculosis, familial Mediterranean fever, rheumatoid arthritis, multiple myeloma or amyloidic mutations of transthyretin and fibrinogen protein.
Causes
Common Causes
In renal amyloidosis, most common causes include:[1]
- Idiopathic ( Primary (AL) amyloidosis )
- Amyloidosis secondary to:
Less Common Causes
In renal amyloidosis, less common causes include:[2]
- .Hereditary amyloidosis due to amyloidogenic mutations:
References
- ↑ Said SM, Sethi S, Valeri AM, Leung N, Cornell LD, Fidler ME, Herrera Hernandez L, Vrana JA, Theis JD, Quint PS, Dogan A, Nasr SH (September 2013). "Renal amyloidosis: origin and clinicopathologic correlations of 474 recent cases". Clin J Am Soc Nephrol. 8 (9): 1515–23. doi:10.2215/CJN.10491012. PMC 3805078. PMID 23704299.
- ↑ Mahmood S, Palladini G, Sanchorawala V, Wechalekar A (February 2014). "Update on treatment of light chain amyloidosis". Haematologica. 99 (2): 209–21. doi:10.3324/haematol.2013.087619. PMC 3912950. PMID 24497558.