Renal amyloidosis epidemiology and demographics: Difference between revisions
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{{Renal Amyloidosis}} | {{Renal Amyloidosis}} | ||
{{CMG}}; {{AE}} {{SHH}} | {{CMG}}; {{AE}} {{SHH}} [[User:Okamal|Omer Kamal, M.D.]] [Mailto:okamal@bidmc.harvard.edu| <nowiki>[2]</nowiki>] | ||
==Overview== | ==Overview== | ||
The incidence is 0.97 to 1.4 cases per 100,000 person-years. The prevalence of AL amyloidosis was 40.5 in 2015, an annual percentage change (APC) of 12%. In renal amyloidosis, is usually first diagnosed in average age of 65 years and it is uncommon before age of 40. | |||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
===Incidence=== | ===Incidence=== | ||
The incidence is 0.97 to 1.4 cases per 100,000 person-years.<ref name="pmid29748430">{{cite journal |vauthors=Quock TP, Yan T, Chang E, Guthrie S, Broder MS |title=Epidemiology of AL amyloidosis: a real-world study using US claims data |journal=Blood Adv |volume=2 |issue=10 |pages=1046–1053 |date=May 2018 |pmid=29748430 |pmc=5965052 |doi=10.1182/bloodadvances.2018016402 |url=}}</ref> | |||
===Prevalence=== | ===Prevalence=== | ||
The prevalence of AL amyloidosis was 40.5 in 2015, an annual percentage change (APC) of 12%. <ref name="pmid29748430" /> | |||
===Mortality rate=== | ===Mortality rate=== | ||
* | *AL has higher mortality than AA type<ref name="pmid18184882">{{cite journal |vauthors=Bollée G, Guery B, Joly D, Snanoudj R, Terrier B, Allouache M, Mercadal L, Peraldi MN, Viron B, Fumeron C, Elie C, Fakhouri F |title=Presentation and outcome of patients with systemic amyloidosis undergoing dialysis |journal=Clin J Am Soc Nephrol |volume=3 |issue=2 |pages=375–81 |date=March 2008 |pmid=18184882 |pmc=2390937 |doi=10.2215/CJN.02470607 |url=}}</ref> | ||
===Age=== | ===Age=== | ||
* | * The incidence of renal amyloidosis increases with age; the median age at diagnosis is 65 years.<ref name="pmid25852856">{{cite journal |vauthors=Khalighi MA, Dean Wallace W, Palma-Diaz MF |title=Amyloid nephropathy |journal=Clin Kidney J |volume=7 |issue=2 |pages=97–106 |date=April 2014 |pmid=25852856 |pmc=4377792 |doi=10.1093/ckj/sfu021 |url=}}</ref><ref name="pmid27942184">{{cite journal |vauthors=Hajra A, Bandyopadhyay D |title=An interesting case of renal amyloidosis |journal=Indian J Nephrol |volume=26 |issue=6 |pages=467–469 |date=2016 |pmid=27942184 |pmc=5131391 |doi=10.4103/0971-4065.177143 |url=}}</ref> | ||
===Race=== | ===Race=== | ||
*There is no racial predilection to | *There is no racial predilection to renal amyloidosis. | ||
===Gender=== | ===Gender=== | ||
* | *Males are are more commonly affected by renal amyloidosis. | ||
*The male to female ratio is approximately 2 to 1.<ref name="pmid25852856" /> | |||
===Region=== | ===Region=== | ||
* | *ALECT2 is more frequent in the United States area.<ref name="pmid23704299">{{cite journal |vauthors=Said SM, Sethi S, Valeri AM, Leung N, Cornell LD, Fidler ME, Herrera Hernandez L, Vrana JA, Theis JD, Quint PS, Dogan A, Nasr SH |title=Renal amyloidosis: origin and clinicopathologic correlations of 474 recent cases |journal=Clin J Am Soc Nephrol |volume=8 |issue=9 |pages=1515–23 |date=September 2013 |pmid=23704299 |pmc=3805078 |doi=10.2215/CJN.10491012 |url=}}</ref> | ||
*AFib cases are most reported in Europe countries. | |||
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==References== | ==References== | ||
Latest revision as of 15:50, 9 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2] Omer Kamal, M.D. [2]
Overview
The incidence is 0.97 to 1.4 cases per 100,000 person-years. The prevalence of AL amyloidosis was 40.5 in 2015, an annual percentage change (APC) of 12%. In renal amyloidosis, is usually first diagnosed in average age of 65 years and it is uncommon before age of 40.
Epidemiology and Demographics
Incidence
The incidence is 0.97 to 1.4 cases per 100,000 person-years.[1]
Prevalence
The prevalence of AL amyloidosis was 40.5 in 2015, an annual percentage change (APC) of 12%. [1]
Mortality rate
- AL has higher mortality than AA type[2]
Age
- The incidence of renal amyloidosis increases with age; the median age at diagnosis is 65 years.[3][4]
Race
- There is no racial predilection to renal amyloidosis.
Gender
- Males are are more commonly affected by renal amyloidosis.
- The male to female ratio is approximately 2 to 1.[3]
Region
- ALECT2 is more frequent in the United States area.[5]
- AFib cases are most reported in Europe countries.
References
- ↑ 1.0 1.1 Quock TP, Yan T, Chang E, Guthrie S, Broder MS (May 2018). "Epidemiology of AL amyloidosis: a real-world study using US claims data". Blood Adv. 2 (10): 1046–1053. doi:10.1182/bloodadvances.2018016402. PMC 5965052. PMID 29748430.
- ↑ Bollée G, Guery B, Joly D, Snanoudj R, Terrier B, Allouache M, Mercadal L, Peraldi MN, Viron B, Fumeron C, Elie C, Fakhouri F (March 2008). "Presentation and outcome of patients with systemic amyloidosis undergoing dialysis". Clin J Am Soc Nephrol. 3 (2): 375–81. doi:10.2215/CJN.02470607. PMC 2390937. PMID 18184882.
- ↑ 3.0 3.1 Khalighi MA, Dean Wallace W, Palma-Diaz MF (April 2014). "Amyloid nephropathy". Clin Kidney J. 7 (2): 97–106. doi:10.1093/ckj/sfu021. PMC 4377792. PMID 25852856.
- ↑ Hajra A, Bandyopadhyay D (2016). "An interesting case of renal amyloidosis". Indian J Nephrol. 26 (6): 467–469. doi:10.4103/0971-4065.177143. PMC 5131391. PMID 27942184.
- ↑ Said SM, Sethi S, Valeri AM, Leung N, Cornell LD, Fidler ME, Herrera Hernandez L, Vrana JA, Theis JD, Quint PS, Dogan A, Nasr SH (September 2013). "Renal amyloidosis: origin and clinicopathologic correlations of 474 recent cases". Clin J Am Soc Nephrol. 8 (9): 1515–23. doi:10.2215/CJN.10491012. PMC 3805078. PMID 23704299.