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{{Small intestine cancer}}
{{Small intestine cancer}}
{{CMG}}
{{CMG}}; {{AE}}{{Qurrat}}, {{PSD}}
==Overview==
==Overview==
Common risk factors in the development of small intestine cancer are [[Crohn's disease]], [[celiac disease]], [[radiation exposure]], hereditary cancer syndromes, [[smoking]], and [[alcohol]].
==Risk Factors==
==Risk Factors==
Risk factors for small intestine cancer include<ref>Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C. Pathogenesis and risk factors of small bowel adenocarcinoma: a colorectal cancer sibling? Am J Gastroenterol. 2005 Mar;100(3):703-10. PMID 15743371.</ref><ref>Chen AC, Neugut AI. Malignant Neoplasms of the Small Intestine. eMedicine.com. URL: [http://www.emedicine.com/MED/topic2651.htm http://www.emedicine.com/MED/topic2651.htm]. Accessed on: June 2, 2006.</ref>:
*There are no established risk factors of small intestinal cancers.
*[[Crohn's disease]]  
*However, there are some associations and most common association is [[Crohn's disease]].
*[[Celiac disease]]
* Other associated factors are described below.
*[[Radiation exposure]]
*Hereditary GI cancer syndromes: [[familial adenomatous polyposis]], [[hereditary nonpolyposis colorectal cancer]], [[Peutz-Jeghers syndrome]]
*[[Male]]


[[Benign tumour]]s and conditions that may be mistaken for cancer of the small bowel:
===Common risk factors===
*[[Hamartoma]]
*[[Crohn disease]] is considered to be the most important risk factor of small intestinal cancers.<ref name="pmid15274064">{{cite journal |vauthors=Dabaja BS, Suki D, Pro B, Bonnen M, Ajani J |title=Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients |journal=Cancer |volume=101 |issue=3 |pages=518–26 |date=August 2004 |pmid=15274064 |doi=10.1002/cncr.20404 |url=}}</ref>
*[[Tuberculosis]]
 
===Less common risk factors===
*Other associated risk factors are:<ref name="pmid29498365">{{cite journal |vauthors=Sarosiek T, Stelmaszuk M |title=[Small intestine neoplasms] |language=Polish |journal=Pol. Merkur. Lekarski |volume=44 |issue=260 |pages=45–48 |date=February 2018 |pmid=29498365 |doi= |url=}}</ref><ref>Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C. Pathogenesis and risk factors of small bowel adenocarcinoma: a colorectal cancer sibling? Am J Gastroenterol. 2005 Mar;100(3):703-10. PMID 15743371.</ref>
**[[Familial Adenomatous Polyposis]] (FAP)
**[[Lynch syndrome]]
**[[Acquired immunodeficiency syndrome]] (AIDS)
**[[Celiac disease]]
**[[Peutz-Jeghers Syndrome]]
**[[Hereditary nonpolyposis colorectal neoplasms]]
**[[Radiation exposure]]
**Hereditary cancer syndromes
***[[Familial adenomatous polyposis]]
***[[Hereditary nonpolyposis colorectal cancer]]
***[[Peutz-Jeghers syndrome]]
***MUTYH-associated polyposis
**[[Smoking]] and [[alcohol]] use increases the risk of small intestine cancer
**[[Colon cancer]]: Survivors of [[Colon (anatomy)|colon]] cancer have an increased risk of getting cancer of the [[small intestine]]


==References==
==References==
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[[Category:Disease]]
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[[Category:Medicine]]
[[Category:Gastroenterology]]
[[Category:Surgery]]

Latest revision as of 19:49, 14 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Parminder Dhingra, M.D. [3]

Overview

Common risk factors in the development of small intestine cancer are Crohn's disease, celiac disease, radiation exposure, hereditary cancer syndromes, smoking, and alcohol.

Risk Factors

  • There are no established risk factors of small intestinal cancers.
  • However, there are some associations and most common association is Crohn's disease.
  • Other associated factors are described below.

Common risk factors

  • Crohn disease is considered to be the most important risk factor of small intestinal cancers.[1]

Less common risk factors

References

  1. Dabaja BS, Suki D, Pro B, Bonnen M, Ajani J (August 2004). "Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients". Cancer. 101 (3): 518–26. doi:10.1002/cncr.20404. PMID 15274064.
  2. Sarosiek T, Stelmaszuk M (February 2018). "[Small intestine neoplasms]". Pol. Merkur. Lekarski (in Polish). 44 (260): 45–48. PMID 29498365.
  3. Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C. Pathogenesis and risk factors of small bowel adenocarcinoma: a colorectal cancer sibling? Am J Gastroenterol. 2005 Mar;100(3):703-10. PMID 15743371.

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