Small intestine cancer surgery: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Small intestine cancer}} | {{Small intestine cancer}} | ||
{{CMG}}{{AE}}{{Qurrat}} {{PSD}} | {{CMG}}; {{AE}}{{Qurrat}}, {{PSD}} | ||
==Overview== | ==Overview== | ||
Curative surgery is the primary modality for treating small intestine cancers, in combination with chemotherapy and radiotherapy. | Curative surgery is the primary modality for treating [[Small intestine cancer|small intestine cancers]], in combination with [[chemotherapy]] and [[radiotherapy]]. | ||
==Indications== | |||
* Primary treatment for cancer of the [[small intestine]] is curative surgical resection.<ref name="pmid20871040">{{cite journal |vauthors=Higashi D, Ishibashi Y, Tamura T, Nii K, Egawa Y, Koga M, Tomiyasu T, Harimura T, Tanaka R, Futatsuki R, Noda S, Futami K, Maekawa T, Takaki Y, Hirai F, Matsui T |title=Clinical features of and chemotherapy for cancer of the small intestine |journal=Anticancer Res. |volume=30 |issue=8 |pages=3193–7 |date=August 2010 |pmid=20871040 |doi= |url=}}</ref><ref name="pmid11982470">{{cite journal |vauthors=Talamonti MS, Goetz LH, Rao S, Joehl RJ |title=Primary cancers of the small bowel: analysis of prognostic factors and results of surgical management |journal=Arch Surg |volume=137 |issue=5 |pages=564–70; discussion 570–1 |date=May 2002 |pmid=11982470 |doi= |url=}}</ref> | |||
==Surgery== | == Surgery == | ||
*For non-metastatic disease curative surgery gives good results, when done in a [[Tertiary care|tertiary care center]].<ref name="pmid15274064">{{cite journal |vauthors=Dabaja BS, Suki D, Pro B, Bonnen M, Ajani J |title=Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients |journal=Cancer |volume=101 |issue=3 |pages=518–26 |date=August 2004 |pmid=15274064 |doi=10.1002/cncr.20404 |url=}}</ref> | |||
*[[Adenocarcinoma]] of [[duodenum]] has a comparative low 5-year disease free [[survival rate]] after surgery.<ref name="pmid15274064">{{cite journal |vauthors=Dabaja BS, Suki D, Pro B, Bonnen M, Ajani J |title=Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients |journal=Cancer |volume=101 |issue=3 |pages=518–26 |date=August 2004 |pmid=15274064 |doi=10.1002/cncr.20404 |url=}}</ref> | |||
*Although surgical resection of [[Small intestine cancer|small intestinal cancer]] plays an important role in the treatment, 5 yr [[survival rate]] is low even after surgery.<ref name="pmid20496543">{{cite journal |vauthors=Coco C, Rizzo G, Manno A, Mattana C, Verbo A |title=Surgical treatment of small bowel neoplasms |journal=Eur Rev Med Pharmacol Sci |volume=14 |issue=4 |pages=327–33 |date=April 2010 |pmid=20496543 |doi= |url=}}</ref> | |||
*'''Small intestine resection''': In this operation, surgeon removes the piece of intestine that has the tumor and some of the normal tissue on each side of the tumor. | |||
*'''[[Palliative therapy|Palliative operation]]:''' If small intestine cancer has spread too far in the abdomen, the surgeon will do a palliative operation. | |||
*The goal of [[Palliative therapy|palliative resection]] is to decrease symptoms such as abdominal pain and [[abdominal distension]]. | |||
*For tumors of [[jejunum]] and [[ileum]] and [[wide local excision]] to remove the tumor may be done.<ref name="urlAdenocarcinoma of the small bowel - Surgical Treatment - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK6933/ |title=Adenocarcinoma of the small bowel - Surgical Treatment - NCBI Bookshelf |format= |work= |accessdate=}}</ref> | |||
*For [[duodenal cancer]] Whipple's procedure may be done. | |||
==Contraindications== | |||
== | |||
*Surgery is usually reserved for patients with resectable tumors.<ref name="urlAdenocarcinoma of the small bowel - Surgical Treatment - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK6933/ |title=Adenocarcinoma of the small bowel - Surgical Treatment - NCBI Bookshelf |format= |work= |accessdate=}}</ref> | *Surgery is usually reserved for patients with resectable tumors.<ref name="urlAdenocarcinoma of the small bowel - Surgical Treatment - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK6933/ |title=Adenocarcinoma of the small bowel - Surgical Treatment - NCBI Bookshelf |format= |work= |accessdate=}}</ref> | ||
*Tumors | *Tumors for which surgery can not be done, [[Palliative therapy|palliative surgery]] is another option. | ||
==References== | ==References== | ||
Latest revision as of 16:30, 22 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Parminder Dhingra, M.D. [3]
Overview
Curative surgery is the primary modality for treating small intestine cancers, in combination with chemotherapy and radiotherapy.
Indications
- Primary treatment for cancer of the small intestine is curative surgical resection.[1][2]
Surgery
- For non-metastatic disease curative surgery gives good results, when done in a tertiary care center.[3]
- Adenocarcinoma of duodenum has a comparative low 5-year disease free survival rate after surgery.[3]
- Although surgical resection of small intestinal cancer plays an important role in the treatment, 5 yr survival rate is low even after surgery.[4]
- Small intestine resection: In this operation, surgeon removes the piece of intestine that has the tumor and some of the normal tissue on each side of the tumor.
- Palliative operation: If small intestine cancer has spread too far in the abdomen, the surgeon will do a palliative operation.
- The goal of palliative resection is to decrease symptoms such as abdominal pain and abdominal distension.
- For tumors of jejunum and ileum and wide local excision to remove the tumor may be done.[5]
- For duodenal cancer Whipple's procedure may be done.
Contraindications
- Surgery is usually reserved for patients with resectable tumors.[5]
- Tumors for which surgery can not be done, palliative surgery is another option.
References
- ↑ Higashi D, Ishibashi Y, Tamura T, Nii K, Egawa Y, Koga M, Tomiyasu T, Harimura T, Tanaka R, Futatsuki R, Noda S, Futami K, Maekawa T, Takaki Y, Hirai F, Matsui T (August 2010). "Clinical features of and chemotherapy for cancer of the small intestine". Anticancer Res. 30 (8): 3193–7. PMID 20871040.
- ↑ Talamonti MS, Goetz LH, Rao S, Joehl RJ (May 2002). "Primary cancers of the small bowel: analysis of prognostic factors and results of surgical management". Arch Surg. 137 (5): 564–70, discussion 570–1. PMID 11982470.
- ↑ 3.0 3.1 Dabaja BS, Suki D, Pro B, Bonnen M, Ajani J (August 2004). "Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients". Cancer. 101 (3): 518–26. doi:10.1002/cncr.20404. PMID 15274064.
- ↑ Coco C, Rizzo G, Manno A, Mattana C, Verbo A (April 2010). "Surgical treatment of small bowel neoplasms". Eur Rev Med Pharmacol Sci. 14 (4): 327–33. PMID 20496543.
- ↑ 5.0 5.1 "Adenocarcinoma of the small bowel - Surgical Treatment - NCBI Bookshelf".