POEMS syndrome MRI: Difference between revisions
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{{POEMS syndrome}} | {{POEMS syndrome}} | ||
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==Overview== | |||
[[Magnetic resonance imaging|MRI]] may be helpful in the [[diagnosis]] of POEMS [[syndrome]]. Findings on [[Magnetic resonance imaging|MRI]] suggestive of POEMS [[syndrome]] include diffuse lumbosacral [[nerve root]] enhancement on [[Spinal cord|spinal]] [[imaging]], [[bone]] [[lesions]], [[hepatomegaly]] and [[splenomegaly]] on [[Abdomen|abdominal]] [[imaging]], and on [[brain]] [[imaging]], hyperintense [[Lesion|lesions]] in the regions of periventricular and [[Cerebral cortex|subcortical]] [[white matter]] and [[thalamus]]. | |||
==MRI== | |||
[[Magnetic resonance imaging|MRI]] may be helpful in the [[diagnosis]] of POEMS [[syndrome]]. Findings on [[Magnetic resonance imaging|MRI]] suggestive of POEMS [[syndrome]] include: | |||
'''CNS''' | |||
*Hyperintense [[Lesion|lesions]] in the regions of [[Ventricle (brain)|periventricular]] and [[Cerebral cortex|subcortical]] [[white matter]] and [[thalamus]]<ref name="pmid25888197">{{cite journal |vauthors=Güneş HN, Bilecenoğlu NT, Şener U, Yoldaş TK |title=POEMS syndrome with peripheral and central nervous system demyelination: case report |journal=Neurologist |volume=19 |issue=4 |pages=101–3 |date=April 2015 |pmid=25888197 |doi=10.1097/NRL.0000000000000017 |url=}}</ref> | |||
*Diffuse lumbosacral [[nerve root]] enhancement<ref name="pmid28566158">{{cite journal |vauthors=Li Y, Valent J, Soltanzadeh P, Thakore N, Katirji B |title=Diagnostic challenges in POEMS syndrome presenting with polyneuropathy: A case series |journal=J. Neurol. Sci. |volume=378 |issue= |pages=170–174 |date=July 2017 |pmid=28566158 |doi=10.1016/j.jns.2017.05.019 |url=}}</ref> | |||
'''Musculoskeletal''' | |||
*[[Bone]] [[lesions]] with low signal intensity<ref name="pmid26221290">{{cite journal |vauthors=Shi XF, Hu SD, Li JM, Luo XF, Long ZB, Zhu Y, Xi XD |title=Multimodal imaging and clinical characteristics of bone lesions in POEMS syndrome |journal=Int J Clin Exp Med |volume=8 |issue=5 |pages=7467–76 |date=2015 |pmid=26221290 |pmc=4509235 |doi= |url=}}</ref> | |||
'''Abdominal''' | |||
*[[Hepatomegaly]] | |||
*[[Splenomegaly]] | |||
==Images== | |||
[[Image:Spinal nerve root enhancement MRI.png|300px|left|thumb|MRI showing spinal nerve root enhancement. [https://radiopaedia.org/articles/nerve-root-enhancement?lang=us Source: Case courtesy of A.Prof Frank Gaillard, Radiopaedia.org, rID: 44859)]]] | |||
[[Image:Splenomegaly MRI.jpg|300px|center|thumb|MRI showing splenomegaly. [https://radiopaedia.org Source: Case courtesy of Dr Michael Sargent, Radiopaedia.org, rID: 6002]]] | |||
==References== | ==References== | ||
Latest revision as of 05:17, 8 February 2019
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POEMS syndrome Microchapters |
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POEMS syndrome MRI On the Web |
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American Roentgen Ray Society Images of POEMS syndrome MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]
Overview
MRI may be helpful in the diagnosis of POEMS syndrome. Findings on MRI suggestive of POEMS syndrome include diffuse lumbosacral nerve root enhancement on spinal imaging, bone lesions, hepatomegaly and splenomegaly on abdominal imaging, and on brain imaging, hyperintense lesions in the regions of periventricular and subcortical white matter and thalamus.
MRI
MRI may be helpful in the diagnosis of POEMS syndrome. Findings on MRI suggestive of POEMS syndrome include:
CNS
- Hyperintense lesions in the regions of periventricular and subcortical white matter and thalamus[1]
- Diffuse lumbosacral nerve root enhancement[2]
Musculoskeletal
Abdominal
Images
References
- ↑ Güneş HN, Bilecenoğlu NT, Şener U, Yoldaş TK (April 2015). "POEMS syndrome with peripheral and central nervous system demyelination: case report". Neurologist. 19 (4): 101–3. doi:10.1097/NRL.0000000000000017. PMID 25888197.
- ↑ Li Y, Valent J, Soltanzadeh P, Thakore N, Katirji B (July 2017). "Diagnostic challenges in POEMS syndrome presenting with polyneuropathy: A case series". J. Neurol. Sci. 378: 170–174. doi:10.1016/j.jns.2017.05.019. PMID 28566158.
- ↑ Shi XF, Hu SD, Li JM, Luo XF, Long ZB, Zhu Y, Xi XD (2015). "Multimodal imaging and clinical characteristics of bone lesions in POEMS syndrome". Int J Clin Exp Med. 8 (5): 7467–76. PMC 4509235. PMID 26221290.