VIPoma other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
Other diagnostic studies for VIPoma include immunohistochemical staining test, which demonstrates staining for markers such as [[chromogranin A]], [[Cytokeratin|cytokeratin 19]], [[synaptophysin]], [[Ki-67]], [[Enolase|neuron specific enolase]], PGP 9.5. | Other [[diagnostic studies]] for VIPoma include immunohistochemical staining test, which demonstrates staining for markers such as [[chromogranin A]], [[Cytokeratin|cytokeratin 19]], [[synaptophysin]], [[Ki-67]], [[Enolase|neuron specific enolase]], PGP 9.5. | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
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[[Category:Medicine]] | [[Category:Medicine]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Up-To-Date]] | [[Category:Up-To-Date]] | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] |
Latest revision as of 00:40, 30 July 2020
VIPoma Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2] Homa Najafi, M.D.[3]
Overview
Other diagnostic studies for VIPoma include immunohistochemical staining test, which demonstrates staining for markers such as chromogranin A, cytokeratin 19, synaptophysin, Ki-67, neuron specific enolase, PGP 9.5.
Other Diagnostic Studies
- Immunohistochemical staining may be helpful in the diagnosis of VIPoma. Findings suggestive of VIPoma include positive histochemical staining for:[1]
- Chromogranin A
- Cytokeratin 19 positive stain is an independent marker of aggressive behavior in pancreatic neuroendocrine tumors.
- Synaptophysin
- Ki-67 (indicates the percentage of neoplastic cells immunolabeled for the marker of proliferation Ki67)
- NSE (neuron-specific enolase)
- PGP 9.5 (protein gene product 9.5)
References
- ↑ Chetty R (2008). "An overview of practical issues in the diagnosis of gastroenteropancreatic neuroendocrine pathology". Arch Pathol Lab Med. 132 (8): 1285–9. doi:10.1043/1543-2165(2008)132[1285:AOOPII]2.0.CO;2. PMID 18684027.