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{{Chest pain}}
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==Overview==
==Overview==
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==Causes==
===Life Threatening Causes<ref name="pmid27981367">{{cite journal| author=Wächter C, Markus B, Schieffer B| title=[Cardiac causes of chest pain]. | journal=Internist (Berl) | year= 2017 | volume= 58 | issue= 1 | pages= 8-21 | pmid=27981367 | doi=10.1007/s00108-016-0165-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27981367 }}</ref>===
===Life Threatening Causes<ref name="pmid27981367">{{cite journal| author=Wächter C, Markus B, Schieffer B| title=[Cardiac causes of chest pain]. | journal=Internist (Berl) | year= 2017 | volume= 58 | issue= 1 | pages= 8-21 | pmid=27981367 | doi=10.1007/s00108-016-0165-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27981367 }}</ref><ref name="HoorwegWillemsen2017">{{cite journal|last1=Hoorweg|first1=Beatrijs BN|last2=Willemsen|first2=Robert TA|last3=Cleef|first3=Lotte E|last4=Boogaerts|first4=Tom|last5=Buntinx|first5=Frank|last6=Glatz|first6=Jan FC|last7=Dinant|first7=Geert Jan|title=Frequency of chest pain in primary care, diagnostic tests performed and final diagnoses|journal=Heart|volume=103|issue=21|year=2017|pages=1727–1732|issn=1355-6037|doi=10.1136/heartjnl-2016-310905 }}</ref>===
*[[Aortic dissection]]<ref name="pmid28871571">{{cite journal| author=Gawinecka J, Schönrath F, von Eckardstein A| title=Acute aortic dissection: pathogenesis, risk factors and diagnosis. | journal=Swiss Med Wkly | year= 2017 | volume= 147 | issue= | pages= w14489 | pmid=28871571 | doi=10.4414/smw.2017.14489 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28871571 }}</ref>
*[[Aortic dissection]]<ref name="pmid28871571">{{cite journal| author=Gawinecka J, Schönrath F, von Eckardstein A| title=Acute aortic dissection: pathogenesis, risk factors and diagnosis. | journal=Swiss Med Wkly | year= 2017 | volume= 147 | issue= | pages= w14489 | pmid=28871571 | doi=10.4414/smw.2017.14489 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28871571 }}</ref>
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aisha Adigun, B.Sc., M.D. [2] , Kiran Singh, M.D. [3] ,Nuha Al-Howthi, MD [4]
Overview Life threatening causes of chest pain include myocardial infarction , aortic dissection , pulmonary embolism , tension pneumothorax , and esophageal rupture . Other common causes of chest pain include GERD , chest wall tenderness, achalasia , pneumonia , and anxiety .
Causes Life Threatening Causes[ 1] [ 2] Common Causes[ 6] [ 7] Causes by Organ System
Cardiovascular
Accelerated hypertension , acute aortic dissection , acute coronary syndrome , aortic aneurysm , aortic coarctation , aortic Stenosis , arryhthmias , atheroma , atrial fibrillation , atrial flutter , atrial myxoma , Bergman syndrome, Bernheim syndrome, Bland-White-Garland Syndrome , cardiac syndrome X , cardiomyopathy , cardiopulmonary resuscitation , chronic stable angina , cor pulmonale , coronary artery dissection , coronary heart disease , dilated cardiomyopathy , Dressler's syndrome , Eisenmenger syndrome , familial hypercholesterolemia , heart attack , Heller-dohle disease , hypertrophic cardiomyopathy , ischemic heart disease , isolated coronary artery anomalies , Kawasaki disease , left ventricular hypertrophy , mitral valve prolapse , myocardial infarction myocarditis , non ST elevation MI , pericardial tamponade , pericarditis , prinzmetal angina , pulmonary embolism , ST elevation MI , stress cardiomyopathy , Takotsubos cardiomyopathy , unstable angina
Chemical/Poisoning
1,1-Dimethyl hydrazine , 1,2-Dibromo-3-chloropropane , acetonitrile , acrylonitrile , arsenic dioxide , arsenicals , carbon monoxide , lead
Dental
No underlying causes
Dermatologic
Herpes zoster , SAPHO syndrome
Drug Side Effect
Adenosine , amonafide , amphetamine , aztreonam , bedaquiline fumarate , cidofovir , clomifene , corticorelin , cytarabine , cytosine arabinoside syndrome desmopressin , dimercaprol , disulfiram , dolasetron mesylate , dornase Alfa , febuxostat , fesoterodine , gemeprost , glatiramer acetate , idarubicin hydrochloride , indomethacin , interferon gamma , iodixanol , ivacaftor , latanoprost , levalbuterol , megestrol , meropenem ,nylidrin , methacholine , nabilone , naratriptan , Oprelvekin , phenylephrine , porfimer , porfimer ,regadenoson , ramucirumab , repaglinide , repaglinide and metformin hydrochloride , rifaximin , rizatriptan , sargramostim , sertraline , sumatriptan , taliglucerase alfa , tamsulosin , thalidomide , tiagabine , tolmetin , topiramate , travoprost , triazolam , trospium , zolmitriptan , zonisamide
Ear Nose Throat
Retropharyngeal abscess
Endocrine
Acromegaly , conn's Syndrome , gynecomastia , hyperthyroidism , hypothyroidism
Environmental
No underlying causes
Gastroenterologic
Abdominal distension , achalasia , Barret’s esophagus , Bergman syndrome, cholecystitis , cholelithiasis , diverticulitis , duodenitis , esophageal cyst , esophageal rupture , esophageal spasm , esophagitis , foreign body , gallbladder disease , gas , gastritis ,gastroesophageal reflux (GERD ), hiatus hernia , impacted stone , irritable bowel disease , liver abscess , Mallory-Weiss Syndrome , neoplasm ,nutcracker's esophagus , pancreatitis , peptic ulcer disease , perforated ulcer , peritonitis , Plummer-Vinson Syndrome , pneumoperitoneum rumination disorder , splenic enlargement , splenic infarction , subdiaphragmatic abcsess , subphrenic abscess , Whipple's Disease
Genetic
Fabry disease , familial hypercholesterolemia , familial mediterranean fever , recurrent hereditary polyserositis
Hematologic
Acute intermittent porphyria , autoimmune hemolytic anemia , blood transfusion complication , langerhans' cell histiocytosis , lymphangiomyomatosis , pulmonary embolism , sickle cell anemia
Iatrogenic
No underlying causes
Infectious Disease
Alveolar hydatid disease , ankylostomiasis , Bornholm disease , chagas disease , cryptococcosis , hepatitis , herpes zoster , Herpes zoster ,Actinomyces , histoplasmosis , HIV infection , lassa fever , Legionnaires' disease , mycoplasma pneumonia , peritonitis , pneumonia , Pott's Disease , Subdiaphragmatic abcsess , trichinella spiralis
Musculoskeletal/Orthopedic
SAPHO syndrome , Ankylosing spondylitis , Bechterew's Disease , chest wall pain syndrome , chondritis , costosternal tendinitis , connective tissue disease , chondritis , costochondritis , costochondrol tendinitis , degenerative changes of cervical spine , fibromyalgia , fractured rib , intercostal muscle spasm , intercostal neuralgia , interstitial fibrosis , muscle strain or spasm , musculoskeletal pain , myofascial pain , myostitis , Pectus excavatum , periostitis , precordial catch syndrome shoulder bursitis , radiculitis , rib pain , SAPHO syndrome , shoulder tendinitis , Soft tissue sarcoma or tumor , sternoclavicular arthritis , strain of pectoralis muscle , thoracic outlet syndrome , Tietze's syndrome , vertebrogenic thoracic pain , xiphodynia
Neurologic
Acute spinal cord injury , migraine headache , neuritis , shingles , tabes dorsalis
Nutritional/Metabolic
Glycogenosis
Obstetric/Gynecologic
Mastalgia , Mondor's disease , thelarche
Oncologic
Bone tumor , bronchial carcinoma , bronchogenic carcinoma , liver cancer , langerhans' cell histiocytosis , mediastinal tumor , mesothelioma , metastatic tumor , neurofibroma , pheochromocytoma , pleural fibroma
Ophthalmologic
No underlying causes
Overdose/Toxicity
No underlying causes
Psychiatric
Affective disorders (e.g., anxiety disorders , chronic fatigue syndrome , Da costa's syndrome , depression ), fabricated or induced illness , factitious disorders (e.g. münchausen syndrome , fixed delusions ) hyperventilation syndrome , functional disorders , hospital addiction syndrome , hypochondria , panic attack , somatization disorder , somatoform disorders , thought disorders
Pulmonary
Alveolar hydatid disease anthracosis , asbestosis , asthma , barotrauma , bronchial carcinoma , bronchiectasis , bronchitis , bronchogenic carcinoma , bronchogenic cyst , chronic cough , chronic obstructive pulmonary disease (COPD ), cor pulmonale , empyema , foreign body aspiration Goodpasture's syndrome , hemothorax , hyperventilation , Interstitial lung disease , laryngotracheitis , legionnaires' disease , lung abscess , lung Cancer , lymphoma , mediastinitis , mesothelioma , mycoplasma pneumonia , pleural effusion , pleural empyema , pleural fibroma , pleuritis ,pleurodynia , pneumoconiosis , pneumomediastinum , pneumonia , pneumothorax , pulmonary embolism , pulmonary infarction , respiratory alkalosis ,silicosis , tension pneumothorax , thymoma , tracheitis , tracheoesophageal abscess , tuberculosis , wegner's granulomatosis
Renal/Electrolyte
Goodpasture's syndrome , Wegner's granulomatosis
Rheumatology/Immunology/Allergy
Atopy , autoimmune hemolytic anemia , chondritis , connective tissue disease , costochondritis , degenerative changes of cervical spine , familial mediterranean fever , fibromyalgia , Goodpasture's syndrome , langerhans' cell histiocytosis , recurrent hereditary polyserositis , Wegner's granulomatosis
Sexual
No underlying causes
Trauma
Acute spinal cord injury , barotrauma , chest wall injuries
Urologic
No underlying causes
Miscellaneous
Air embolism ,Chinese restaurant syndrome , decompression sickness , Idiopathic
References
↑ Wächter C, Markus B, Schieffer B (2017). "[Cardiac causes of chest pain]" . Internist (Berl) . 58 (1): 8–21. doi :10.1007/s00108-016-0165-0 . PMID 27981367 . ↑ Hoorweg, Beatrijs BN; Willemsen, Robert TA; Cleef, Lotte E; Boogaerts, Tom; Buntinx, Frank; Glatz, Jan FC; Dinant, Geert Jan (2017). "Frequency of chest pain in primary care, diagnostic tests performed and final diagnoses". Heart . 103 (21): 1727–1732. doi :10.1136/heartjnl-2016-310905 . ISSN 1355-6037 . ↑ Gawinecka J, Schönrath F, von Eckardstein A (2017). "Acute aortic dissection: pathogenesis, risk factors and diagnosis" . Swiss Med Wkly . 147 : w14489. doi :10.4414/smw.2017.14489 . PMID 28871571 . ↑ Hoorweg BB, Willemsen RT, Cleef LE, Boogaerts T, Buntinx F, Glatz JF; et al. (2017). "Frequency of chest pain in primary care, diagnostic tests performed and final diagnoses" . Heart . 103 (21): 1727–1732. doi :10.1136/heartjnl-2016-310905 . PMID 28634285 . ↑ Swierzy M, Helmig M, Ismail M, Rückert J, Walles T, Neudecker J (2014). "[Pneumothorax]" . Zentralbl Chir . 139 Suppl 1: S69–86, quiz S87. doi :10.1055/s-0034-1383029 . PMID 25264729 . ↑ Lenfant C (2010). "Chest pain of cardiac and noncardiac origin" . Metabolism . 59 Suppl 1: S41–6. doi :10.1016/j.metabol.2010.07.014 . PMID 20837193 . ↑ Jany B (2017). "[Pulmonary causes of chest pain]" . Internist (Berl) . 58 (1): 22–28. doi :10.1007/s00108-016-0169-9 . PMID 27986981 .