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==Overview==
==Overview==
Haff disease has an incubation period of eight hours, and presents with nausea, vomiting, muscle rigidity, chest pain, diaphoresis, and brown urine. Though it is a self limiting condition with good prognosis, some cases may develop complication such as acute kidney injury, and disseminated intravascular coagulation.
Haff disease has an incubation period of eight hours and presents with nausea, vomiting, muscle rigidity, chest pain, diaphoresis, and brown urine. Though it is a self-limiting condition with a good prognosis, some cases may develop complications such as acute kidney injury and disseminated intravascular coagulation.


==Natural history, Complications and Prognosis==
==Natural history, Complications and Prognosis==
As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed.  Early diagnosis and treatment are required to prevent the development of complications.  
*As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed.  Early diagnosis and treatment are required to prevent the development of complications.  


It has an incubation period of eight hours, and presents with nausea, vomiting, myalgias, muscle rigidity, chest pain (mimicking [[myocardial infarction]]), diaphoresis, dyspnea, and brown urine indicating [[myoglobinuria]].  As it is a self limiting condition with good prognosis, most patients recover in 2-5 days.  Haff disease is rarely associated with mortality, but some cases may develop complications such as [[acute kidney injury]], and [[disseminated intravascular coagulation]]. <ref name="pmid25978748">{{cite journal| author=Diaz J| title=Don't be Half-Educated About Haff Disease in Louisiana. | journal=J La State Med Soc | year= 2015 | volume= 167 | issue= 1 | pages= 6-10 | pmid=25978748 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25978748  }} </ref>  <ref name="pmid28846335">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume=  | issue=  | pages=  | pmid=28846335 | doi= | pmc= | url= }} </ref>
*It has an incubation period of eight hours and presents with nausea, vomiting, myalgias, muscle rigidity, chest pain (mimicking [[myocardial infarction]]), diaphoresis, dyspnea, and brown urine indicating [[myoglobinuria]].  As it is a self limiting condition with good prognosis, most patients recover in 2-5 days.  Haff disease is rarely associated with mortality, but some cases may develop complications such as [[acute kidney injury]] and [[disseminated intravascular coagulation]]. <ref name="pmid25978748">{{cite journal| author=Diaz J| title=Don't be Half-Educated About Haff Disease in Louisiana. | journal=J La State Med Soc | year= 2015 | volume= 167 | issue= 1 | pages= 6-10 | pmid=25978748 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25978748  }} </ref>  <ref name="pmid28846335">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume=  | issue=  | pages=  | pmid=28846335 | doi= | pmc= | url= }} </ref>


==References==
==References==
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[[Category:Disease]]
[[Category:Disease]]
[[Category:Syndromes]]
[[Category:Syndromes]]
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Latest revision as of 13:19, 27 April 2022

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S

Overview

Haff disease has an incubation period of eight hours and presents with nausea, vomiting, muscle rigidity, chest pain, diaphoresis, and brown urine. Though it is a self-limiting condition with a good prognosis, some cases may develop complications such as acute kidney injury and disseminated intravascular coagulation.

Natural history, Complications and Prognosis

  • As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed. Early diagnosis and treatment are required to prevent the development of complications.

References

  1. Diaz J (2015). "Don't be Half-Educated About Haff Disease in Louisiana". J La State Med Soc. 167 (1): 6–10. PMID 25978748.
  2. "StatPearls". 2022. PMID 28846335.