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==Overview==
Haff disease has an incubation period of eight hours and presents with nausea, vomiting, muscle rigidity, chest pain, diaphoresis, and brown urine. Though it is a self-limiting condition with a good prognosis, some cases may develop complications such as acute kidney injury and disseminated intravascular coagulation.
 
==Natural history, Complications and Prognosis==
*As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosedEarly diagnosis and treatment are required to prevent the development of complications.
 
*It has an incubation period of eight hours and presents with nausea, vomiting, myalgias, muscle rigidity, chest pain (mimicking [[myocardial infarction]]), diaphoresis, dyspnea, and brown urine indicating [[myoglobinuria]]. As it is a self limiting condition with good prognosis, most patients recover in 2-5 days. Haff disease is rarely associated with mortality, but some cases may develop complications such as [[acute kidney injury]] and [[disseminated intravascular coagulation]]. <ref name="pmid25978748">{{cite journal| author=Diaz J| title=Don't be Half-Educated About Haff Disease in Louisiana. | journal=J La State Med Soc | year= 2015 | volume= 167 | issue= 1 | pages= 6-10 | pmid=25978748 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25978748  }} </ref>  <ref name="pmid28846335">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume=  | issue=  | pages= | pmid=28846335 | doi= | pmc= | url= }} </ref>


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==References==
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Latest revision as of 13:19, 27 April 2022

Haff disease Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S

Overview

Haff disease has an incubation period of eight hours and presents with nausea, vomiting, muscle rigidity, chest pain, diaphoresis, and brown urine. Though it is a self-limiting condition with a good prognosis, some cases may develop complications such as acute kidney injury and disseminated intravascular coagulation.

Natural history, Complications and Prognosis

  • As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed. Early diagnosis and treatment are required to prevent the development of complications.

References

  1. Diaz J (2015). "Don't be Half-Educated About Haff Disease in Louisiana". J La State Med Soc. 167 (1): 6–10. PMID 25978748.
  2. "StatPearls". 2022. PMID 28846335.