Liposarcoma CT: Difference between revisions
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==Overview== | ==Overview== | ||
CT imaging is | CT imaging is crucial for the diagnosis of liposarcoma. CT scan may detect regions of lipid and non-lipid components that correlate with histological subtypes of liposarcoma. CT imaging may demonstrate the size, location, and depth of a liposarcoma, as well as [[lymph node]] involvement and distant [[metastasis]]. CT findings may be correlated with the [[histopathological]] subtype. | ||
==CT Scan== | ==CT Scan== | ||
* The appearance and morphologic relationship | * A CT image commonly detects areas of focal or diffuse infiltration of lipid and non-lipid components. | ||
* CT scan | * The appearance and morphologic relationship between the lipid and non-lipid components of a liposarcoma on CT scan frequently help in identifying the specific histologic subtype of liposarcoma.<ref name="KimMurakami1996">{{cite journal|last1=Kim|first1=T|last2=Murakami|first2=T|last3=Oi|first3=H|last4=Tsuda|first4=K|last5=Matsushita|first5=M|last6=Tomoda|first6=K|last7=Fukuda|first7=H|last8=Nakamura|first8=H|title=CT and MR imaging of abdominal liposarcoma.|journal=American Journal of Roentgenology|volume=166|issue=4|year=1996|pages=829–833|issn=0361-803X|doi=10.2214/ajr.166.4.8610559}}</ref> | ||
* CT scan also determines the size and depth of the tumor, stage of the disease, presence of lymphadenopathy, and evidence of distal metastasis.<ref name="KumarasamyGayer2011">{{cite journal|last1=Kumarasamy|first1=Narmadan A.|last2=Gayer|first2=Gabriela|title=Retroperitoneal Sarcomas|journal=Seminars in Ultrasound, CT and MRI|volume=32|issue=5|year=2011|pages=422–432|issn=08872171|doi=10.1053/j.sult.2011.06.002}}</ref> | |||
====CT Findings According to the Liposarcoma Subtype==== | ====CT Findings According to the Liposarcoma Subtype==== | ||
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| style="padding: 5px 5px; background: #F5F5F5;" colspan=7|<small> Table adapted from | | style="padding: 5px 5px; background: #F5F5F5;" colspan=7|<small> Table adapted from Lu J, Qin Q, Zhan LL, et al. Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma. ''Asian Pac J Cancer Prev''. 2014;15(15):6041-6.<ref>{{Cite journal | ||
| author = [[Jing Lu]], [[Qin Qin]], [[Liang-Liang Zhan]], [[Xi Yang]], [[Qing Xu]], [[Jing Yu]], [[Li-Na Dou]], [[Hao Zhang]], [[Yan Yang]], [[Xiao-Chen Chen]], [[Yue-Hua Yang]], [[Hong-Yan Cheng]] & [[Xin-Chen Sun]] | | author = [[Jing Lu]], [[Qin Qin]], [[Liang-Liang Zhan]], [[Xi Yang]], [[Qing Xu]], [[Jing Yu]], [[Li-Na Dou]], [[Hao Zhang]], [[Yan Yang]], [[Xiao-Chen Chen]], [[Yue-Hua Yang]], [[Hong-Yan Cheng]] & [[Xin-Chen Sun]] | ||
| title = Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma | | title = Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma | ||
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| pmid = 25124571 | | pmid = 25124571 | ||
}}</ref> </small> | }}</ref> </small> | ||
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Latest revision as of 16:53, 27 May 2019
Liposarcoma Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Liposarcoma CT On the Web |
American Roentgen Ray Society Images of Liposarcoma CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
CT imaging is crucial for the diagnosis of liposarcoma. CT scan may detect regions of lipid and non-lipid components that correlate with histological subtypes of liposarcoma. CT imaging may demonstrate the size, location, and depth of a liposarcoma, as well as lymph node involvement and distant metastasis. CT findings may be correlated with the histopathological subtype.
CT Scan
- A CT image commonly detects areas of focal or diffuse infiltration of lipid and non-lipid components.
- The appearance and morphologic relationship between the lipid and non-lipid components of a liposarcoma on CT scan frequently help in identifying the specific histologic subtype of liposarcoma.[1]
- CT scan also determines the size and depth of the tumor, stage of the disease, presence of lymphadenopathy, and evidence of distal metastasis.[2]
CT Findings According to the Liposarcoma Subtype
Subtypes | Density | Margins | Fat Content | Nodular muscle-density area in tumor | Calcifications | Necrotic or cystic areas |
Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) | Fat | Smooth regular | > 65% | ++ | Few/none | + |
Dedifferentiated liposarcoma (DDL) | Mixed | Rough irregular | 30-60% | +++ | Few/none | ++ |
Myxoid/round cell liposarcoma (ML/RCL) | Mixed | Rough irregular | 25-50% | + | Common | +++ |
Pleomorphic liposarcoma (PL) | Soft tissue | Incomplete irregular | 6-25% | + | Few/none | + |
Mixed-type liposarcoma | Mixed | Smooth regular | 30-60% | ++ | Common | + |
Table adapted from Lu J, Qin Q, Zhan LL, et al. Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma. Asian Pac J Cancer Prev. 2014;15(15):6041-6.[3] |
References
- ↑ Kim, T; Murakami, T; Oi, H; Tsuda, K; Matsushita, M; Tomoda, K; Fukuda, H; Nakamura, H (1996). "CT and MR imaging of abdominal liposarcoma". American Journal of Roentgenology. 166 (4): 829–833. doi:10.2214/ajr.166.4.8610559. ISSN 0361-803X.
- ↑ Kumarasamy, Narmadan A.; Gayer, Gabriela (2011). "Retroperitoneal Sarcomas". Seminars in Ultrasound, CT and MRI. 32 (5): 422–432. doi:10.1053/j.sult.2011.06.002. ISSN 0887-2171.
- ↑ Jing Lu, Qin Qin, Liang-Liang Zhan, Xi Yang, Qing Xu, Jing Yu, Li-Na Dou, Hao Zhang, Yan Yang, Xiao-Chen Chen, Yue-Hua Yang, Hong-Yan Cheng & Xin-Chen Sun (2014). "Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma". Asian Pacific journal of cancer prevention : APJCP. 15 (15): 6041–6046. PMID 25124571.