Latest revision as of 19:06, 29 May 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

MRI is the optimal imaging test for the diagnosis of liposarcoma. MRI findings for a well-differentiated liposarcoma include a mass with at least 75% of adipose content with thin irregular septa. MRI also evaluates the size, location, and depth of the mass. MRI findings help to differentiate between the different sub-types of liposarcoma and also help to assess distant metastasis.

MRI

MRI findings for a well-differentiated liposarcoma include a mass with at least 75% of adipose content with thin irregular septa.^[1]
Other sub-types may demonstrate fewer adipose content.
Thick septa inside the mass are associated with a malignant disease and poorer prognosis.
Hemorrhage and necrosis may be observed within the mass among patients with the de-differentiated sub-type of liposarcoma.
Typically, myxoid liposarcoma has a low signal intensity on T1, in contrast to well-differentiated liposarcoma which has a high intensity signal on T1 due to the presence of high adipose content.^[2]
The myxoid sub-type may be associated with a cystic appearance on MRI among approximately 20% of cases. The myxoid sub-type may also appear multilobulated. ^[3]

Images

Myxoid Liposarcoma: Large soft tissue mass is noted at the medial posterior portion of the lower part of the left thigh. It has an isointense signal to the adjacent muscles on T1 sequences with an area of high signal intensity which is suppressed by STIR sequences indicating fatty component. It appears intermediate in signal intensity on T2 sequences with intense enhancement post-gadolinium injection.
Image courtesy of Radiopaedia.org

References

	Liposarcoma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Liposarcoma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Liposarcoma MRI On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Liposarcoma MRI All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Liposarcoma MRI
CDC on Liposarcoma MRI
Liposarcoma MRI in the news
Blogs on Liposarcoma MRI
Directions to Hospitals Treating Liposarcoma
Risk calculators and risk factors for Liposarcoma MRI

↑ Peterson, Jeffrey J.; Kransdorf, Mark J.; Bancroft, Laura W.; O'Connor, Mary I. (2003). "Malignant fatty tumors: classification, clinical course, imaging appearance and treatment". Skeletal Radiology. 32 (9): 493–503. doi:10.1007/s00256-003-0647-8. ISSN 0364-2348.
↑ M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter |month= ignored (help)
↑ M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter |month= ignored (help)

Template:WikiDoc Sources

[PetersonKransdorf2003-1] Peterson, Jeffrey J.; Kransdorf, Mark J.; Bancroft, Laura W.; O'Connor, Mary I. (2003). "Malignant fatty tumors: classification, clinical course, imaging appearance and treatment". Skeletal Radiology. 32 (9): 493–503. doi:10.1007/s00256-003-0647-8. ISSN 0364-2348.

[2] M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter |month= ignored (help)

[3] M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter |month= ignored (help)

[1]

[2]

[3]

@@ Line 4: / Line 4: @@
 ==Overview==
-MRI is the imaging test of choice for the diagnosis of liposarcoma.
+[[Magnetic resonance imaging|MRI]] is the optimal [[imaging]] [[test]] for the [[diagnosis]] of liposarcoma. [[Magnetic resonance imaging|MRI]] findings for a well-differentiated liposarcoma include a mass with at least 75% of [[adipose]] content with thin irregular [[septa]]. [[Magnetic resonance imaging|MRI]] also evaluates the size, location, and depth of the mass. [[Magnetic resonance imaging|MRI]] findings help to differentiate between the different sub-types of liposarcoma and also help to assess distant [[metastasis]].
 ==MRI==
-Tumors like round cell lipoma  are likely to spread towards the bones esspecially spine and pelvis. MRI of the total spine helps to asses this metastasis.
+*[[Magnetic resonance imaging|MRI]] findings for a well-differentiated liposarcoma include a mass with at least 75% of [[adipose]] content with thin irregular [[septa]].<ref name="PetersonKransdorf2003">{{cite journal|last1=Peterson|first1=Jeffrey J.|last2=Kransdorf|first2=Mark J.|last3=Bancroft|first3=Laura W.|last4=O'Connor|first4=Mary I.|title=Malignant fatty tumors: classification, clinical course, imaging appearance and treatment|journal=Skeletal Radiology|volume=32|issue=9|year=2003|pages=493–503|issn=0364-2348|doi=10.1007/s00256-003-0647-8}}</ref>
+*Other sub-types may demonstrate fewer [[adipose]] content.
+*Thick [[septa]] inside the mass are associated with a [[malignant]] [[disease]] and poorer [[prognosis]].
+*[[Hemorrhage]] and [[necrosis]] may be observed within the mass among [[Patient|patients]] with the de-differentiated sub-type of liposarcoma.
+*Typically, myxoid liposarcoma has a low signal intensity on T1, in contrast to well-differentiated liposarcoma which has a high intensity signal on T1 due to the presence of high [[adipose]] content.<ref>{{Cite journal
+| author = [[M. S. Sung]], [[H. S. Kang]], [[J. S. Suh]], [[J. H. Lee]], [[J. M. Park]], [[J. Y. Kim]] & [[H. G. Lee]]
+ | title = Myxoid liposarcoma: appearance at MR imaging with histologic correlation
+ | journal = [[Radiographics : a review publication of the Radiological Society of North America, Inc]]
+ | volume = 20
+ | issue = 4
+ | pages = 1007–1019
+ | year = 2000
+ | month = July-August
+ | doi = 10.1148/radiographics.20.4.g00jl021007
+ | pmid = 10903690
+}}</ref>
+*The myxoid sub-type may be associated with a [[cystic]] appearance on [[Magnetic resonance imaging|MRI]] among approximately 20% of cases. The myxoid sub-type may also appear [[Lobule|multilobulated]]. <ref>{{Cite journal
+| author = [[M. S. Sung]], [[H. S. Kang]], [[J. S. Suh]], [[J. H. Lee]], [[J. M. Park]], [[J. Y. Kim]] & [[H. G. Lee]]
+ | title = Myxoid liposarcoma: appearance at MR imaging with histologic correlation
+ | journal = [[Radiographics : a review publication of the Radiological Society of North America, Inc]]
+ | volume = 20
+ | issue = 4
+ | pages = 1007–1019
+ | year = 2000
+ | month = July-August
+ | doi = 10.1148/radiographics.20.4.g00jl021007
+ | pmid = 10903690
+}}</ref>
+==Images==
+{|
+|[[File: Myxoid Liposarcoma of the Thigh.jpg |thumb|320px|Myxoid Liposarcoma: Large [[soft tissue]] mass is noted at the [[Anatomical terms of location|medial]] [[Anatomical terms of location|posterior]] portion of the lower part of the left [[thigh]]. It has an isointense signal to the adjacent [[Muscle|muscles]] on T1 sequences with an area of high signal intensity which is suppressed by STIR sequences indicating [[Fat|fatty]] component. It appears intermediate in signal intensity on T2 sequences with intense enhancement post-[[gadolinium]] [[Injection (medicine)|injection]]. <br> Image courtesy of Radiopaedia.org]]
+|[[File: Myxoid Liposarcoma of the Thigh 2.jpg |thumb|320px|Myxoid Liposarcoma: Large [[soft tissue]] mass is noted at the [[Anatomical terms of location|medial]] [[Anatomical terms of location|posterior]] portion of the lower part of the left [[thigh]]. It has an isointense signal to the adjacent [[Muscle|muscles]] on T1 sequences with an area of high signal intensity which is suppressed by STIR sequences indicating [[Fat|fatty]] component. It appears intermediate in signal intensity on T2 sequences with intense enhancement post-[[gadolinium]] [[Injection (medicine)|injection]]. <br> Image courtesy of Radiopaedia.org]]
+|[[File: Myxoid Liposarcoma of the Thigh 3.jpg |thumb|320px|Myxoid Liposarcoma: Large [[soft tissue]] mass is noted at the [[Anatomical terms of location|medial]] [[Anatomical terms of location|posterior]] portion of the lower part of the left [[thigh]]. It has an isointense signal to the adjacent [[Muscle|muscles]] on T1 sequences with an area of high signal intensity which is suppressed by STIR sequences indicating [[Fat|fatty]] component. It appears intermediate in signal intensity on T2 sequences with intense enhancement post-[[gadolinium]] [[Injection (medicine)|injection]]. <br> Image courtesy of Radiopaedia.org]]
+|}
-=References==
+=References=
 {{reflist|2}}
 [[Category:Disease]]
 [[Category:Types of cancer]]
-[[Category:Oncology]]
 [[Category:Surgery]]
 {{WikiDoc Help Menu}}
 {{WikiDoc Sources}}
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]

Liposarcoma MRI: Difference between revisions

Latest revision as of 19:06, 29 May 2019

Overview

MRI

Images

References

Navigation menu