Endocarditis physical examination: Difference between revisions

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{{Endocarditis}}
{{Endocarditis}}


{{CMG}}; '''Associate Editors-in-Chief:''' {{CZ}}
{{CMG}}; {{AE}} {{CZ}}


==Overview==
==Overview==
Common signs on physical examination of endocarditis include [[fever]], presence of a new or changing heart [[murmur]], [[rigors]],  [[Osler's nodes]], [[Janeway lesions]] and evidence of embolization.<ref name=abc> Infective endocarditis. Wikipedia (2015). URL=https://en.wikipedia.org/wiki/Infective_endocarditis#Pathogenesis Accessed on September 23, 2015</ref>  [[Aortic insufficiency]] with a [[wide pulse pressure]], [[mitral regurgitation]] or [[tricuspid regurgitation]] may be present depending upon the valve that is infected.<ref name=abc> Infective endocarditis. Wikipedia (2015). URL=https://en.wikipedia.org/wiki/Infective_endocarditis#Pathogenesis Accessed on September 23, 2015</ref><ref name="Baddour-2005">{{Cite journal  | last1 = Baddour | first1 = LM. | last2 = Wilson | first2 = WR. | last3 = Bayer | first3 = AS. | last4 = Fowler | first4 = VG. | last5 = Bolger | first5 = AF. | last6 = Levison | first6 = ME. | last7 = Ferrieri | first7 = P. | last8 = Gerber | first8 = MA. | last9 = Tani | first9 = LY. | title = Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America. | journal = Circulation | volume = 111 | issue = 23 | pages = e394-434 | month = Jun | year = 2005 | doi = 10.1161/CIRCULATIONAHA.105.165564 | PMID = 15956145 }}</ref>
Common signs on physical examination of [[endocarditis]] include [[fever]], presence of a new or changing heart [[murmur]], [[rigors]],  [[Osler's nodes]], [[Janeway lesions]] and evidence of [[embolization]]. [[Aortic insufficiency]] with a [[wide pulse pressure]], [[mitral regurgitation]] or [[tricuspid regurgitation]] may be present depending upon the valve that is infected.


==Vital Signs==
==Physical Examination==
 
===Appearance of the Patient===
*Patients with [[endocarditis]] usually appear ill.<ref name="Baddour-2005">{{Cite journal  | last1 = Baddour | first1 = LM. | last2 = Wilson | first2 = WR. | last3 = Bayer | first3 = AS. | last4 = Fowler | first4 = VG. | last5 = Bolger | first5 = AF. | last6 = Levison | first6 = ME. | last7 = Ferrieri | first7 = P. | last8 = Gerber | first8 = MA. | last9 = Tani | first9 = LY. | title = Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America. | journal = Circulation | volume = 111 | issue = 23 | pages = e394-434 | month = Jun | year = 2005 | doi = 10.1161/CIRCULATIONAHA.105.165564 | PMID = 15956145 }}</ref><ref name="pmid19797553">{{cite journal| author=Lockhart PB, Brennan MT, Thornhill M, Michalowicz BS, Noll J, Bahrani-Mougeot FK et al.| title=Poor oral hygiene as a risk factor for infective endocarditis-related bacteremia. | journal=J Am Dent Assoc | year= 2009 | volume= 140 | issue= 10 | pages= 1238-44 | pmid=19797553 | doi= | pmc=PMC2770162 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19797553  }} </ref>
 
===Vital Signs===
* A [[fever]] will likely be present.
* A [[fever]] will likely be present.
* [[Rigors]] may be present.
* [[Rigors]] may be present.
* Some patients may have a wide [[pulse pressure]] due to [[aortic insufficiency]]. If the pulse pressure narrows, this may be a sign of [[left ventricular failure]] due to earlier closure of the mitral valve and a more rapid rise in the left ventricular end diastolic pressure which will in turn raise the diastolic pressure.
* Some patients may have a wide [[pulse pressure]] due to [[aortic insufficiency]]. If the [[pulse pressure]] narrows, this may be a sign of [[left ventricular failure]] due to earlier closure of the [[mitral valve]] and a more rapid rise in the left [[ventricular]] end [[diastolic pressure]] which will in turn raise the [[diastolic pressure]].


==Skin==
===Skin===
*[[Petechiae]] are present in 10% to 40% of patients
*[[Petechiae]] are present in 10% to 40% of patients
*[[Splinter hemorrhages]] are present in 5% to 15% of patients
*[[Splinter hemorrhages]] are present in 5% to 15% of patients
*[[Osler's nodes]] which are tender subcutaneous nodules in pulp of digits are present in 7% to 10% of patients
*[[Osler's nodes]] which are tender [[subcutaneous]] [[Nodule (medicine)|nodules]] in pulp of [[digits]] are present in 7% to 10% of patients
*[[Janeway lesion]]s which are [[erythema]]tous, nontender lesions on palm or sole are present in 6% to 10% of patients
*[[Janeway lesion]]s which are [[erythema]]tous, nontender [[lesions]] on palm or sole are present in 6% to 10% of patients


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==Oral Cavity==
===Oral Cavity===
Examine the oral cavity:
Examine the oral cavity:
* Poor oral hygiene<ref name="pmid19797553">{{cite journal| author=Lockhart PB, Brennan MT, Thornhill M, Michalowicz BS, Noll J, Bahrani-Mougeot FK et al.| title=Poor oral hygiene as a risk factor for infective endocarditis-related bacteremia. | journal=J Am Dent Assoc | year= 2009 | volume= 140 | issue= 10 | pages= 1238-44 | pmid=19797553 | doi= | pmc=PMC2770162 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19797553  }} </ref><br>
* Poor oral [[hygiene]]<br>
* [[Teeth]] looking for [[periodontitis]], [[plaque]] and [[calculus]]<ref name="pmid19797553">{{cite journal| author=Lockhart PB, Brennan MT, Thornhill M, Michalowicz BS, Noll J, Bahrani-Mougeot FK et al.| title=Poor oral hygiene as a risk factor for infective endocarditis-related bacteremia. | journal=J Am Dent Assoc | year= 2009 | volume= 140 | issue= 10 | pages= 1238-44 | pmid=19797553 | doi= | pmc=PMC2770162 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19797553  }} </ref><BR>
* [[Teeth]] looking for [[periodontitis]], [[plaque]] and [[calculus]]<BR>
* [[Gingiva]] looking for [[gingivitis]]<ref name="pmid19797553">{{cite journal| author=Lockhart PB, Brennan MT, Thornhill M, Michalowicz BS, Noll J, Bahrani-Mougeot FK et al.| title=Poor oral hygiene as a risk factor for infective endocarditis-related bacteremia. | journal=J Am Dent Assoc | year= 2009 | volume= 140 | issue= 10 | pages= 1238-44 | pmid=19797553 | doi= | pmc=PMC2770162 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19797553  }} </ref><BR>
* [[Gingiva]] looking for [[gingivitis]]<BR>
* Recent dental procedure
* Recent [[dental]] procedure
 
*
 
===HEENT===


== Eyes==
[[Image:Roth-spot (white-centered hemorrhage - endocarditis).jpg|left|150px|[[Roth's spot]]s (white centered hemorrhage)|thumb]]
*[[Conjunctival hemorrhage]]
*[[Conjunctival hemorrhage]]
*[[Roth's spot]]s in the [[retina]]
*[[Roth's spot]]s in the [[retina]]
<br clear="left"/>
*Bobbing of the [[uvula]] may be present among patients with new onset [[aortic regurgitation]].
 
<br />[[Image:Roth-spot (white-centered hemorrhage - endocarditis).jpg|[[Roth's spot]]s (white centered hemorrhage)|thumb|center|320x320px]]
 
 
 
 
 
 
 
 
 
 
 
<br />
===Neck===


==Ear Nose and Throat==
* Neck examination of patients with [[endocarditis]] is usually normal.
*Bobbing of the [[uvula]] may be present among patients with new onset [[aortic regurgitation]].


==Heart==
===Lungs===
*Heart [[murmur]]s are present in 80% to 85% of patients including that of [[aortic insufficiency]], [[tricuspid regurgitation]] and [[mitral regurgitation]].


==Lungs==
*Signs of [[heart failure]] such as [[rales]] may present
*Signs of [[heart failure]] such as [[rales]] may present


==Abdomen==
===Heart===
* [[Abdominal pain]] may be present due to [[mesenteric embolization]] or [[ileus]] both of which may manifest as [[reduced bowel sounds]]
*Heart [[murmur]]s are present in 80% to 85% of patients including that of [[aortic insufficiency]], [[tricuspid regurgitation]] and [[mitral regurgitation]].<ref name="pmid96368522">{{cite journal| author=John MD, Hibberd PL, Karchmer AW, Sleeper LA, Calderwood SB| title=Staphylococcus aureus prosthetic valve endocarditis: optimal management and risk factors for death. | journal=Clin Infect Dis | year= 1998 | volume= 26 | issue= 6 | pages= 1302-9 | pmid=9636852 | doi=10.1086/516378 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9636852  }}</ref>
 
===Abdomen===
* [[Abdominal pain]] may be present due to [[Mesentery|mesenteric]] [[embolization]] or [[ileus]] both of which may manifest as [[reduced bowel sounds]].
* [[Splenomegaly]] may be present in 15% to 30% patients.
* [[Splenomegaly]] may be present in 15% to 30% patients.
* [[Left upper quadrant pain]] (LUQ pain) may be present as a result of a [[splenic infarct]] from embolization.
* Left upper quadrant pain (LUQ pain) may be present as a result of a [[splenic infarct]] from [[embolization]].
* [[Flank pain]] may be present as a result of an [[embolus to the kidney]]
* [[Flank pain]] may be present as a result of an [[embolus to the kidney]].
 
===Back===
 
* Back examination of patients with [[endocarditis]] is usually normal
 
===Genitourinary===
 
* Genitourinary examination of patients with [[endocarditis]] is usually normal.
 
===Neurologic===


==Extremities==
*[[Septic emboli]] may result in [[stroke]] and focal [[neurologic]] findings<ref name="pmid9636852">{{cite journal| author=John MD, Hibberd PL, Karchmer AW, Sleeper LA, Calderwood SB| title=Staphylococcus aureus prosthetic valve endocarditis: optimal management and risk factors for death. | journal=Clin Infect Dis | year= 1998 | volume= 26 | issue= 6 | pages= 1302-9 | pmid=9636852 | doi=10.1086/516378 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9636852  }}</ref>
* [[Janeway lesion]]s (painless hemorrhagic cutaneous lesions on the palms and soles)
*[[Seizures]] may be present
*[[Intracranial hemorrhage]] may occur
* Signs of a [[brain abscess]] may be present
 
===Extremities===
* [[Janeway lesion]]s (painless [[hemorrhagic]] cutaneous lesions on the palms and soles)
* [[Gangrene]] of fingers may occur
* [[Gangrene]] of fingers may occur
* The fingers may show [[splinter haemorrhage]]s
* The fingers may show [[splinter haemorrhage]]s
* [[Osler's node]]s ([[lesions|painful subcutaneous lesions in the distal fingers]])
* [[Osler's node]]s ([[lesions|painful subcutaneous lesions in the distal fingers]])


==Neurologic==
* [[Septic emboli]] may result in [[stroke]] and focal neurologic findings
* [[Seizures]] may be present
* [[Intracranial hemorrhage]] may occur
* Signs of a [[brain abscess]] may be present


==References==
==References==
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[[Category:Emergency medicine]]
[[Category:Emergency medicine]]
[[Category:Cardiology]]
[[Category:Cardiology]]
[[Category:Infectious disease]]
 
[[Category:Intensive care medicine]]
[[Category:Intensive care medicine]]
[[Category:Up-To-Date]]
[[Category:Up-To-Date]]

Latest revision as of 14:26, 4 March 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

Common signs on physical examination of endocarditis include fever, presence of a new or changing heart murmur, rigors, Osler's nodes, Janeway lesions and evidence of embolization. Aortic insufficiency with a wide pulse pressure, mitral regurgitation or tricuspid regurgitation may be present depending upon the valve that is infected.

Physical Examination

Appearance of the Patient

Vital Signs

Skin

Petechiae
Splinter hemorrhages
Osler's nodes
Janeway lesions

Oral Cavity

Examine the oral cavity:

HEENT


Roth's spots (white centered hemorrhage)







Neck

  • Neck examination of patients with endocarditis is usually normal.

Lungs

Heart

Abdomen

Back

  • Back examination of patients with endocarditis is usually normal

Genitourinary

  • Genitourinary examination of patients with endocarditis is usually normal.

Neurologic

Extremities


References

  1. Baddour, LM.; Wilson, WR.; Bayer, AS.; Fowler, VG.; Bolger, AF.; Levison, ME.; Ferrieri, P.; Gerber, MA.; Tani, LY. (2005). "Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America". Circulation. 111 (23): e394–434. doi:10.1161/CIRCULATIONAHA.105.165564. PMID 15956145. Unknown parameter |month= ignored (help)
  2. Lockhart PB, Brennan MT, Thornhill M, Michalowicz BS, Noll J, Bahrani-Mougeot FK; et al. (2009). "Poor oral hygiene as a risk factor for infective endocarditis-related bacteremia". J Am Dent Assoc. 140 (10): 1238–44. PMC 2770162. PMID 19797553.
  3. John MD, Hibberd PL, Karchmer AW, Sleeper LA, Calderwood SB (1998). "Staphylococcus aureus prosthetic valve endocarditis: optimal management and risk factors for death". Clin Infect Dis. 26 (6): 1302–9. doi:10.1086/516378. PMID 9636852.
  4. John MD, Hibberd PL, Karchmer AW, Sleeper LA, Calderwood SB (1998). "Staphylococcus aureus prosthetic valve endocarditis: optimal management and risk factors for death". Clin Infect Dis. 26 (6): 1302–9. doi:10.1086/516378. PMID 9636852.


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