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==Overview== | ==Overview== | ||
Risk factor for mast cell leukemia is [[systemic mastocytosis]], a premalignant condition. Factors involved in malignant transformation of systemic mastocytosis into mast cell leukemia include [[Age|advanced age]], [[Weight loss|history of weight loss]], [[anemia]], [[thrombocytopenia]], [[hypoalbuminemia]], and an excess of bone marrow blasts. | Risk factor for mast cell leukemia is [[systemic mastocytosis]], a premalignant condition. Factors involved in malignant transformation of systemic mastocytosis into mast cell leukemia include [[Age|advanced age]], [[Weight loss|history of weight loss]], [[anemia]], [[thrombocytopenia]], [[hypoalbuminemia]], and an excess of bone marrow blasts. | ||
==Mast cell leukemia risk factors== | ==Mast cell leukemia risk factors== | ||
Risk factor for mast cell leukemia is [[systemic mastocytosis]], a premalignant condition. | *[[Risk factor]] for mast cell leukemia is [[systemic mastocytosis]], a [[Premalignant condition|premalignant]] condition. | ||
*[[Age|Advanced age]] | *Common risk factors in the development of [[malignant]] transformation of [[systemic mastocytosis]] into mast cell leukemia include:<ref name="Georgin-LavialleLhermitte2012">{{cite journal|last1=Georgin-Lavialle|first1=S.|last2=Lhermitte|first2=L.|last3=Dubreuil|first3=P.|last4=Chandesris|first4=M.-O.|last5=Hermine|first5=O.|last6=Damaj|first6=G.|title=Mast cell leukemia|journal=Blood|volume=121|issue=8|year=2012|pages=1285–1295|issn=0006-4971|doi=10.1182/blood-2012-07-442400}}</ref> | ||
*[[Weight loss|History of weight loss]] | :*[[Age|Advanced age]] | ||
*[[Anemia]] | :*[[Weight loss|History of weight loss]] | ||
*[[Thrombocytopenia]] | :*[[Anemia]] | ||
*[[Hypoalbuminemia]] | :*[[Thrombocytopenia]] | ||
*An excess of bone marrow blasts | :*[[Hypoalbuminemia]] | ||
:*An excess of [[bone marrow]] [[Blast|blasts]] | |||
==References== | ==References== | ||
{{reflist|1}} | {{reflist|1}} | ||
Latest revision as of 17:11, 5 November 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Risk factor for mast cell leukemia is systemic mastocytosis, a premalignant condition. Factors involved in malignant transformation of systemic mastocytosis into mast cell leukemia include advanced age, history of weight loss, anemia, thrombocytopenia, hypoalbuminemia, and an excess of bone marrow blasts.
Mast cell leukemia risk factors
- Risk factor for mast cell leukemia is systemic mastocytosis, a premalignant condition.
- Common risk factors in the development of malignant transformation of systemic mastocytosis into mast cell leukemia include:[1]
References
- ↑ Georgin-Lavialle, S.; Lhermitte, L.; Dubreuil, P.; Chandesris, M.-O.; Hermine, O.; Damaj, G. (2012). "Mast cell leukemia". Blood. 121 (8): 1285–1295. doi:10.1182/blood-2012-07-442400. ISSN 0006-4971.