Hemophilia A secondary prevention: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Hemophilia A}} | {{Hemophilia A}} | ||
{{CMG}} {{FNY}} | {{CMG}}{{AE}}{{FNY}} | ||
==Overview== | ==Overview== | ||
Secondary prevention for | [[Secondary prevention]] for [[Hemophilia A|Hemophilia]] is aimed at preventing spontaneous or excessive bleeds in patients who are high risk, and relies on the use of recombinant clotting [[factor VIII]]/ IX to prevent bleeding episodes. | ||
==Secondary Prevention== | ==Secondary Prevention== | ||
Secondary preventive measures to avoid Hemophilia A include the following: | Secondary preventive measures to avoid Hemophilia A and B include the following: | ||
*Patients should be counseled on safe practices and routine accident prevention. | *Patients should be counseled on safe practices and routine accident prevention. | ||
*Patients with moderate-to-severe hemophilia may be managed with prophylactic transfusions of recombinant clotting factor VIII in order to prevent bleeding episodes. The goal of prophylaxis is usually to keep clotting factor levels at 1 percent or greater at all times. <ref> Prophylaxis: Administration and dosing schedules – World Federation of Hemophilia. Available at http://www.wfh.org/en/abd/prophylaxis/prophylaxis-administration-and-dosing-schedules. Accessed on Sept 20, 2016 </ref> | *Patients with moderate-to-severe hemophilia may be managed with prophylactic transfusions of recombinant clotting factor VIII/ IX in order to prevent bleeding episodes.<ref name="pmid22551339">{{cite journal| author=Franchini M, Mannucci PM| title=Past, present and future of hemophilia: a narrative review. | journal=Orphanet J Rare Dis | year= 2012 | volume= 7 | issue= | pages= 24 | pmid=22551339 | doi=10.1186/1750-1172-7-24 | pmc=3502605 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22551339 }} </ref> The goal of [[prophylaxis]] is usually to keep clotting factor levels at 1 percent or greater at all times.<ref>Prophylaxis: Administration and dosing schedules – World Federation of Hemophilia. Available at http://www.wfh.org/en/abd/prophylaxis/prophylaxis-administration-and-dosing-schedules. Accessed on Sept 20, 2016 </ref> | ||
*Routine prophylactic transfusions are not recommended for patients with mild hemophilia. | *Routine prophylactic transfusions are not recommended for patients with mild hemophilia. | ||
Latest revision as of 16:14, 16 July 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fahd Yunus, M.D. [2]
Overview
Secondary prevention for Hemophilia is aimed at preventing spontaneous or excessive bleeds in patients who are high risk, and relies on the use of recombinant clotting factor VIII/ IX to prevent bleeding episodes.
Secondary Prevention
Secondary preventive measures to avoid Hemophilia A and B include the following:
- Patients should be counseled on safe practices and routine accident prevention.
- Patients with moderate-to-severe hemophilia may be managed with prophylactic transfusions of recombinant clotting factor VIII/ IX in order to prevent bleeding episodes.[1] The goal of prophylaxis is usually to keep clotting factor levels at 1 percent or greater at all times.[2]
- Routine prophylactic transfusions are not recommended for patients with mild hemophilia.
References
- ↑ Franchini M, Mannucci PM (2012). "Past, present and future of hemophilia: a narrative review". Orphanet J Rare Dis. 7: 24. doi:10.1186/1750-1172-7-24. PMC 3502605. PMID 22551339.
- ↑ Prophylaxis: Administration and dosing schedules – World Federation of Hemophilia. Available at http://www.wfh.org/en/abd/prophylaxis/prophylaxis-administration-and-dosing-schedules. Accessed on Sept 20, 2016