B-cell lymphoma physical examination: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{B-cell lymphoma}} | {{B-cell lymphoma}} | ||
{{CMG}} ; {{AE}} {{Adnan Ezici}} | |||
==Overview== | |||
Common physical examination findings of B cell lymphomas include [[Lymphadenopathy|peripheral lymphadenopathy]], [[Lymphadenopathy|central lymphadenopathy]], [[fever]], [[pruritus]], [[pallor]], [[petechiae]], [[jaundice]], chest tenderness, [[abdominal distension]], [[abdominal tenderness]], and [[hepatosplenomegaly]]. | |||
==Physical Examination== | |||
The following physical examination findings may be present among patients with B cell lymphomas:<ref name="pmid32644754">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume= | issue= | pages= | pmid=32644754 | doi= | pmc= | url= }} </ref><ref name="pmid29763144">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume= | issue= | pages= | pmid=29763144 | doi= | pmc= | url= }} </ref><ref name="pmid19999217">{{cite journal| author=Hingorjo MR, Syed S| title=Presentation, staging and diagnosis of lymphoma: a clinical perspective. | journal=J Ayub Med Coll Abbottabad | year= 2008 | volume= 20 | issue= 4 | pages= 100-3 | pmid=19999217 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19999217 }} </ref><ref name="pmid28153383">{{cite journal| author=Armitage JO, Gascoyne RD, Lunning MA, Cavalli F| title=Non-Hodgkin lymphoma. | journal=Lancet | year= 2017 | volume= 390 | issue= 10091 | pages= 298-310 | pmid=28153383 | doi=10.1016/S0140-6736(16)32407-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28153383 }} </ref><ref name="pmid32703953">{{cite journal| author=Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH | display-authors=etal| title=Hodgkin lymphoma. | journal=Nat Rev Dis Primers | year= 2020 | volume= 6 | issue= 1 | pages= 61 | pmid=32703953 | doi=10.1038/s41572-020-0189-6 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32703953 }} </ref> | |||
===Appearance of the Patient=== | |||
*Appearance of the Patients with B cell lymphomas depends on the stage of disease. Patients may present with [[cachexic|cachexia]] in late disease stage. | |||
===Vital Signs=== | |||
*Fever | |||
*[[Tachypnea]] | |||
*Asymmetric pulse | |||
===Skin=== | |||
*Skin examination of patients with B cell lymphomas include: | |||
**[[Pallor]] | |||
**[[Pruritus]] | |||
**[[Petechiae]] | |||
**[[Jaundice]] | |||
===HEENT=== | |||
* Abnormalities of the head/hair may include: | |||
**Icteric sclera | |||
**[[Nystagmus]] | |||
*Patients may develop superior vena cava syndrome, which may present with: | |||
**Swelling of the face | |||
**Facial flushing/redness face or cheeks | |||
**Facial tenderness | |||
**Drooping eyelid | |||
**Swelling around the eye | |||
===Neck=== | |||
*[[Lymphadenopathy|Cervical lymphadenopathy]] | |||
===Lungs=== | |||
*Thoracic masses suggestive of [[Lymphadenopathy|central lymphadenopathy]] | |||
*Chest tenderness | |||
*Pleural effusion may develop, which has signs and symptoms such as: | |||
**[[Wheezing]] | |||
**Decreased breath sounds | |||
**Asymmetric chest expansion | |||
**Hyperresonance lungs on chest auscultation | |||
===Heart=== | |||
*Cardiovascular examination of patients with B cell lymphomas is usually normal. | |||
===Abdomen=== | |||
*Abdominal examination of patients with B cell lymphomas include: | |||
**[[Abdominal distension]] | |||
**[[Abdominal tenderness]] | |||
**[[Hepatosplenomegaly]] | |||
**[[Abdominal mass]]es suggestive of [[Lymphadenopathy|central lymphadenopathy]] | |||
===Back=== | |||
*Back examination of patients with B cell lymphomas is usually normal. | |||
===Genitourinary=== | |||
*Genitourinary examination of patients with B cell lymphomas is usually normal. | |||
===Neuromuscular=== | |||
*Neuromuscular examination of patients with B cell lymphomas is usually normal. | |||
===Extremities=== | |||
*[[Lymphadenopathy|Peripheral lymphadenopathy]] | |||
*Joint pain | |||
*[[Edema]] | |||
*[[Bone fractures]] | |||
===CNS=== | |||
*[[Seizures]] | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] |
Latest revision as of 14:29, 29 June 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D[2]
Overview
Common physical examination findings of B cell lymphomas include peripheral lymphadenopathy, central lymphadenopathy, fever, pruritus, pallor, petechiae, jaundice, chest tenderness, abdominal distension, abdominal tenderness, and hepatosplenomegaly.
Physical Examination
The following physical examination findings may be present among patients with B cell lymphomas:[1][2][3][4][5]
Appearance of the Patient
- Appearance of the Patients with B cell lymphomas depends on the stage of disease. Patients may present with cachexia in late disease stage.
Vital Signs
- Fever
- Tachypnea
- Asymmetric pulse
Skin
HEENT
- Abnormalities of the head/hair may include:
- Icteric sclera
- Nystagmus
- Patients may develop superior vena cava syndrome, which may present with:
- Swelling of the face
- Facial flushing/redness face or cheeks
- Facial tenderness
- Drooping eyelid
- Swelling around the eye
Neck
Lungs
- Thoracic masses suggestive of central lymphadenopathy
- Chest tenderness
- Pleural effusion may develop, which has signs and symptoms such as:
- Wheezing
- Decreased breath sounds
- Asymmetric chest expansion
- Hyperresonance lungs on chest auscultation
Heart
- Cardiovascular examination of patients with B cell lymphomas is usually normal.
Abdomen
- Abdominal examination of patients with B cell lymphomas include:
Back
- Back examination of patients with B cell lymphomas is usually normal.
Genitourinary
- Genitourinary examination of patients with B cell lymphomas is usually normal.
Neuromuscular
- Neuromuscular examination of patients with B cell lymphomas is usually normal.
Extremities
- Peripheral lymphadenopathy
- Joint pain
- Edema
- Bone fractures
CNS
References
- ↑ "StatPearls". 2022. PMID 32644754 Check
|pmid=
value (help). - ↑ "StatPearls". 2022. PMID 29763144.
- ↑ Hingorjo MR, Syed S (2008). "Presentation, staging and diagnosis of lymphoma: a clinical perspective". J Ayub Med Coll Abbottabad. 20 (4): 100–3. PMID 19999217.
- ↑ Armitage JO, Gascoyne RD, Lunning MA, Cavalli F (2017). "Non-Hodgkin lymphoma". Lancet. 390 (10091): 298–310. doi:10.1016/S0140-6736(16)32407-2. PMID 28153383.
- ↑ Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH; et al. (2020). "Hodgkin lymphoma". Nat Rev Dis Primers. 6 (1): 61. doi:10.1038/s41572-020-0189-6. PMID 32703953 Check
|pmid=
value (help).