Liposarcoma risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
Common risk factors in the development of liposarcoma include chemical carcinogens, | Common risk factors in the development of liposarcoma include [[chemical]] [[Carcinogen|carcinogens]], [[radiation]], [[immunodeficiency]], [[genetic disorders]], and [[Viral infection|viral infections]]. | ||
==Risk | ==Risk Factors== | ||
Common [[Risk factor|risk factors]] in the development of liposarcoma are:<ref name="WHO-SOft">{{cite web | title = WHO-Soft tissue tumor | url = http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb5/bb5-classifsofttissue.pdf }}</ref><ref name="WHO-SOft">{{cite web | title = WHO-Soft tissue tumor | url = http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb5/bb5-classifsofttissue.pdf }}</ref> | |||
*Chemical carcinogens | *[[Chemical]] [[Carcinogen|carcinogens]] | ||
**Phenoxyacetic herbicides | **[[Herbicide|Phenoxyacetic herbicides]] | ||
**Chlorophenols | **Chlorophenols | ||
**Dioxin | **[[Dioxin]] [[contamination]] | ||
**[[Arsenic]] | **[[Arsenic]] | ||
**[[Thorium dioxide | **[[Thorium dioxide|Thorium dioxide (Thorotrast)]] | ||
*Radiation | *[[Radiation]] | ||
**Risk | **Risk is associated with [[adjuvant therapy]] of [[radiation]] for [[breast carcinoma]]. | ||
**Risk increases with [[dose]] and a [[dose]] of 50 GY or more of [[radiation]] has been recorded with increased risk of [[sarcoma]]. | |||
**The [[mean]] period between exposure to [[Radiation therapy|radiation]] and [[tumor]] [[diagnosis]] is 10 years. | |||
*Immunodeficiency | *[[Immunodeficiency]] | ||
**Regional acquired [[immunodeficiency]] is sometimes associated with liposarcoma | **Regional acquired [[immunodeficiency]] is sometimes associated with liposarcoma. | ||
*Genetic susceptibility | *[[Genetic]] susceptibility | ||
**[[Li-Fraumeni syndrome]] | **[[Li-Fraumeni syndrome]] | ||
**[[Neurofibromatosis | **[[Neurofibromatosis|Neurofibromatosis (NF1; von Recklinghausen disease)]] | ||
**[[Gardner syndrome | **[[Gardner syndrome|Gardner syndrome (Familial adenomatous polyposis)]] | ||
**[[Retinoblastoma]] | **[[Retinoblastoma]] | ||
**[[Werner syndrome]] | **[[Werner syndrome]] | ||
**[[Basal cell carcinoma|Nevoid basal cell carcinoma | **[[Basal cell carcinoma|Nevoid basal cell carcinoma (Gorlin syndrome)]] | ||
*[[Viral infection| | *[[Viral infection|Viral infections]] | ||
==References== | ==References== | ||
Latest revision as of 16:08, 24 May 2019
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Liposarcoma risk factors On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Common risk factors in the development of liposarcoma include chemical carcinogens, radiation, immunodeficiency, genetic disorders, and viral infections.
Risk Factors
Common risk factors in the development of liposarcoma are:[1][1]
- Immunodeficiency
- Regional acquired immunodeficiency is sometimes associated with liposarcoma.
- Genetic susceptibility
References
- ↑ 1.0 1.1 "WHO-Soft tissue tumor" (PDF).