Polymyalgia rheumatica causes: Difference between revisions
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==Overview== | ==Overview== | ||
There is no specific cause for polymyalgia rheumatica. However, there are possible theories about the causes which include [[Inflammation|inflammatory]] joint lining attack, [[Virus|viral infections]], and [[Biological inheritance|genetic inheritance]] of [[HLA-DR4]]. | |||
==Causes== | ==Causes== | ||
*The specific cause of polymyalgia rheumatica is unknown or not well understood. | *The specific cause of polymyalgia rheumatica is unknown or not well understood. | ||
*Possible theories about the causes include the following:<ref name="pmid28600350">{{cite journal| author=Belkhir R, Burel SL, Dunogeant L, Marabelle A, Hollebecque A, Besse B et al.| title=Rheumatoid arthritis and polymyalgia rheumatica occurring after immune checkpoint inhibitor treatment. | journal=Ann Rheum Dis | year= 2017 | volume= 76 | issue= 10 | pages= 1747-1750 | pmid=28600350 | doi=10.1136/annrheumdis-2017-211216 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28600350 }}</ref> | *Possible theories about the causes include the following:<ref name="pmid28600350">{{cite journal| author=Belkhir R, Burel SL, Dunogeant L, Marabelle A, Hollebecque A, Besse B et al.| title=Rheumatoid arthritis and polymyalgia rheumatica occurring after immune checkpoint inhibitor treatment. | journal=Ann Rheum Dis | year= 2017 | volume= 76 | issue= 10 | pages= 1747-1750 | pmid=28600350 | doi=10.1136/annrheumdis-2017-211216 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28600350 }}</ref> | ||
**Inflammatory attack of the joints' lining | **[[Inflammation|Inflammatory]] attack of the joints' lining | ||
**Viral infection (eg, Adenovirus) stimulating the immune system causing autoimmune attack to the joints | **[[Infection|Viral infection]] (eg, ''[[Adenoviridae|Adenovirus]]'') stimulating the [[immune system]] causing [[Autoimmunity|autoimmune]] attack to the joints | ||
**Genetic inheritance of HLA-DR4 subtype | **[[Biological inheritance|Genetic inheritance]] of [[HLA-DR4]] subtype | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Medicine]] | |||
[[Category:Rheumatology]] | |||
[[Category:Up-To-Date]] | |||
Latest revision as of 23:47, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
There is no specific cause for polymyalgia rheumatica. However, there are possible theories about the causes which include inflammatory joint lining attack, viral infections, and genetic inheritance of HLA-DR4.
Causes
- The specific cause of polymyalgia rheumatica is unknown or not well understood.
- Possible theories about the causes include the following:[1]
- Inflammatory attack of the joints' lining
- Viral infection (eg, Adenovirus) stimulating the immune system causing autoimmune attack to the joints
- Genetic inheritance of HLA-DR4 subtype
References
- ↑ Belkhir R, Burel SL, Dunogeant L, Marabelle A, Hollebecque A, Besse B; et al. (2017). "Rheumatoid arthritis and polymyalgia rheumatica occurring after immune checkpoint inhibitor treatment". Ann Rheum Dis. 76 (10): 1747–1750. doi:10.1136/annrheumdis-2017-211216. PMID 28600350.