Adrenal insufficiency classification: Difference between revisions
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{{Adrenal insufficiency}} | {{Adrenal insufficiency}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{Ayeesha}} | ||
==Overview== | ==Overview== | ||
[[Adrenal insufficiency]] may be classified according to location of pathology into three subtypes [[primary adrenal insufficiency]], [[secondary adrenal insufficiency]], and [[tertiary adrenal insufficiency]]. | |||
==Classification== | ==Classification== | ||
[[Adrenal Insufficiency]] may be classified according to location of pathology into three subtypes: | |||
*[[Primary adrenal insufficiency]] | |||
*[[Secondary adrenal insufficiency]] | |||
*[[Tertiary adrenal insufficiency]] | |||
*[ | |||
*[ | |||
*[ | |||
In [[Primary adrenal insufficiency]], the primary pathology lies in the [[adrenal glands]] leading to decreased production of [[cortisol]], [[aldosterone]] and [[androgens]]. Although, the [[androgen]] deficiency manifests only in females as the [[adrenal gland]] is the only source of [[androgens]] in females. [[Secondary adrenal insufficiency]] and [[tertiary adrenal insufficiency]] are subclassified together as [[central adrenal insufficiency]]. In [[Secondary adrenal insufficiency]] the pathology lies in the [[pituitary gland]] leading to reduced production of [[ACTH]]. Whereas, in [[tertiary adrenal insufficiency]] the pathology lies in the [[hypothalamus]] leading to reduced production of [[CRH]]. <ref name="pmid25905309">{{cite journal| author=Feingold KR, Anawalt B, Boyce A, Chrousos G, de Herder WW, Dungan K | display-authors=etal| title=Endotext | journal= | year= 2000 | volume= | issue= | pages= | pmid=25905309 | doi= | pmc= | url= }} </ref> | |||
==References== | ==References== | ||
Latest revision as of 17:14, 22 October 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ayeesha Kattubadi, M.B.B.S[2]
Overview
Adrenal insufficiency may be classified according to location of pathology into three subtypes primary adrenal insufficiency, secondary adrenal insufficiency, and tertiary adrenal insufficiency.
Classification
Adrenal Insufficiency may be classified according to location of pathology into three subtypes:
In Primary adrenal insufficiency, the primary pathology lies in the adrenal glands leading to decreased production of cortisol, aldosterone and androgens. Although, the androgen deficiency manifests only in females as the adrenal gland is the only source of androgens in females. Secondary adrenal insufficiency and tertiary adrenal insufficiency are subclassified together as central adrenal insufficiency. In Secondary adrenal insufficiency the pathology lies in the pituitary gland leading to reduced production of ACTH. Whereas, in tertiary adrenal insufficiency the pathology lies in the hypothalamus leading to reduced production of CRH. [1]