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{{Adrenal insufficiency}}
{{Adrenal insufficiency}}
{{CMG}}; {{AE}} {{Ayeesha}}
{{CMG}}; {{AE}} {{Ayeesha}}  
 
'''Synonyms and keywords:''' Addison's disease
==[[Adrenal insufficiency overview|Overview]]==
==[[Adrenal insufficiency overview|Overview]]==


==[[Adrenal insufficiency historical perspective|Historical Perspective]]==
==[[Adrenal insufficiency historical perspective|Historical Perspective]]==
==Classification==
[['''Adrenal insufficiency''']] is classified based on the location of the [[pathology]] into:
*'''[[Primary adrenal insufficiency]]''' ([[Addison's disease]]).
*'''[[Secondary adrenal insufficiency]]'''.
*'''Tertiary [[adrenal insufficiency]]'''.
In [[Primary adrenal insufficiency]], the [[pathology]] lies in the [[adrenal glands]]. The most common cause of [[primary adrenal insufficiency]] is [[autoimmune adrenalitis]]. In [[secondary adrenal insufficiency]], the [[pathology]] lies in the [[pituitary gland]], whereas in [[tertiary adrenal insufficiency]] the [[pathology]] lies in the [[hypothalamus]]. The most common cause of [[tertiary adrenal insufficiency]] is chronic [[glucocorticoid]] therapy. Secondary and tertiary [[adrenal insufficiency]] together are categorised into central [[adrenal insufficiency]]. The following table summaries the causes of adrenal insufficiency.
{| class="wikitable"
|+
! colspan="3" |Causes of adrenal insufficiency
|-
|Primary adrenal insufficiency
(Addison's disease)
|Secondary adrenal insufficiency
|Tertiary adrenal insufficiency
|-
|
*'''Autoimmune:'''
**Sporadic
**Autoimmune polyendocrine syndrome type 1<br>(APS type 1)
**Autoimmune polyendocrine syndrome type 2<br>(Schmidt's syndrome)
*'''Infections:'''
**Tuberculosis,
**Fungal infections,
**Cytomegalovirus,
**HIV
*'''Adrenal Metastasis'''
*'''Adrenal infiltration'''
*'''Adrenal hemorrhage:'''
**Waterhouse-Friderichsen syndrome,
**Drugs - Anticogulants- Heparin, Warfarin)
*'''Adrenoleukodystrophy'''
*'''Congenital adrenal hypoplasia'''


|
==[[Adrenal insufficiency classification|Classification]]==
|
|}


==[[Adrenal insufficiency pathophysiology|Pathophysiology]]==
==[[Adrenal insufficiency pathophysiology|Pathophysiology]]==


==[[Adrenal insufficiency causes|Causes]]==
==[[Adrenal insufficiency differential diagnosis|Differential diagnosis]]==
 
==[[Adrenal insufficiency differential diagnosis|Differentiating Xyz from other Diseases]]==
 
==[[Adrenal insufficiency epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Adrenal insufficiency risk factors|Risk Factors]]==
 
==[[Adrenal insufficiency screening|Screening]]==


==[[Adrenal insufficiency natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==[[Adrenal insufficiency epidemiology and demographics |Epidemiology and Demographics]]==
==[[Adrenal insufficiency risk factors | Risk factors]]==
==[[Adrenal insufficiency screening | Screening]]==
==[[Adrenal insufficiency natural history, complications and prognosis | Natural History, Complications and Prognosis]]==


==Diagnosis==
==Diagnosis==
[[Adrenal insufficiency diagnostic study of choice|Diagnostic study of choice]] | [[Adrenal insufficiency history and symptoms|History and Symptoms]] | [[Adrenal insufficiency physical examination|Physical Examination]] | [[Adrenal insufficiency laboratory findings|Laboratory Findings]] | [[Adrenal insufficiency electrocardiogram|Electrocardiogram]] | [[Adrenal insufficiency x ray|X-Ray Findings]] | [[Adrenal insufficiency echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Adrenal insufficiency CT scan|CT-Scan Findings]] | [[Adrenal insufficiency MRI|MRI Findings]] | [[Adrenal insufficiency other imaging findings|Other Imaging Findings]] | [[Adrenal insufficiency other diagnostic studies|Other Diagnostic Studies]]
[[Adrenal insufficiency diagnostic study of choice|Diagnostic study of choice]] | [[Adrenal insufficiency history and symptoms|History and Symptoms]] | [[Adrenal insufficiency physical examination|Physical Examination]] | [[Adrenal insufficiency laboratory findings|Laboratory Findings]] | [[Adrenal insufficiency electrocardiogram|Electrocardiogram]] | [[Adrenal insufficiency x ray|X-Ray Findings]] | [[Adrenal insufficiency echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Adrenal insufficiency CT scan|CT Scan Findings]] | [[Adrenal insufficiency MRI|MRI Findings]] | [[Adrenal insufficiency other imaging findings|Other Imaging Findings]] | [[Adrenal insufficiency other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
[[Adrenal insufficiency medical therapy|Medical Therapy]] | [[Adrenal insufficiency interventions|Interventions]] | [[Adrenal insufficiency surgery|Surgery]] | [[Adrenal insufficiency primary prevention|Primary Prevention]] | [[Adrenal insufficiency secondary prevention|Secondary Prevention]] | [[Adrenal insufficiency cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Adrenal insufficiency future or investigational therapies|Future or Investigational Therapies]]


==Case Studies==
[[Adrenal insufficiency medical therapy|Medical Therapy]] | [[Adrenal insufficiency surgery|Surgery]] | [[Adrenal insufficiency primary prevention|Primary Prevention]] | [[Adrenal insufficiency secondary prevention|Secondary Prevention]] | [[Adrenal insufficiency cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Adrenal insufficiency future or investigational therapies|Future or Investigational Therapies]]
[[Adrenal insufficiency case study one|Case #1]]


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Latest revision as of 15:26, 21 January 2021

Adrenal insufficiency Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Xyz from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Interventions

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ayeesha Kattubadi, M.B.B.S[2]

Synonyms and keywords: Addison's disease

Overview

Historical Perspective

Classification

Pathophysiology

Differential diagnosis

Epidemiology and Demographics

Risk factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X-Ray Findings | Echocardiography and Ultrasound | CT Scan Findings | MRI Findings | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

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